ReviewBiology2025
Application of Natural Antioxidants as Feed Additives in Aquaculture: A Review.
Review in Biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Probiotics and prebiotics as alternatives to antibiotics in aquaculture: a systematic and bibliometric review of antimicrobial and antioxidant mechanisms.Frontiers in microbiology · 2026Pooled it
- Postbiotics enhance immune competence in black rockfish (Sebastes schlegelii): linking innate immunity, apoptosis, and resistance to bacterial infection.Journal of animal science and biotechnology · 2026Article
- Bioactive Effects of Astragalus aureus Willd. Extracts on Antioxidant and Antimicrobial Properties and Shelf-Life Extension of Fish Fillets.Applied biochemistry and biotechnology · 2026Article
- Dietary watermelon (Citrullus lanatus) rind mitigates nickel- and copper-induced hepatic, metabolic, and nrf2/keap1 signaling disruptions in Nile tilapia (Oreochromis niloticus).Veterinary research communications · 2026Article
- Synergistic Effects of Ultrasound and Chia Seed Oil on Yak Myofibrillar Protein Gelation: Structure and Gel Property.Foods (Basel, Switzerland) · 2026Article
- Natural Antioxidants and Aquatic Animal Health-2nd Edition.Antioxidants (Basel, Switzerland) · 2026Article
- Trophic Antioxidant Transfer as a Measure for Scalable Coral Conservation Strategies.Antioxidants (Basel, Switzerland) · 2026Article
- Resveratrol as a Bioactive Compound for Edible Fish Muscle Quality: Emerging Evidence, Putative Mechanisms, and Future Perspectives.Foods (Basel, Switzerland) · 2026Review
- Functional Aquafeeds for Climate-Resilient Finfish Culture: A PRISMA-Guided Systematic Evidence Map of Nutritional Strategies for Thermal-Stress Tolerance, Immunity and Metabolic Homeostasis.Veterinary sciences · 2026Review
- Intrinsic Antioxidant Capacity of Fish Muscle as Potential Link Between Pre-Harvest Biology andAntioxidants (Basel, Switzerland) · 2026Review
- Feeding Habits of Narrow-Clawed CrayfishAnimals : an open access journal from MDPI · 2026Article
- Antioxidants and Aquaculture: A Synergistic Approach for Sustainable Aquatic Production.Antioxidants (Basel, Switzerland) · 2026Article
- Article
- Mild oxidative stress and dietary epigenetic modulators direct DNA methylation remodeling toward stress-resilience pathways.BMC genomics · 2026Article
- Nutritional detoxification strategies in aquaculture: bioactive feed additives mitigating oxidative stress and xenobiotic toxicity in fish.Fish physiology and biochemistry · 2026Review
- Microalgae-based aquafeeds for penaeid shrimp: progress toward improved growth, immune modulation, and sustainable production.Veterinary research communications · 2026Review
- Potential role of dietary red onion peel polyphenol-rich extract in enhancing growth, feed utilization, and antioxidant and immune responses in Nile tilapia (Oreochromis niloticus) cultured at high stocking density.Fish physiology and biochemistry · 2026Article
- Sand Substrate Thickness Regulates Growth Performance, Intestinal Antioxidant Defense, and Gut Microbiota in an Experimental Culture ofAnimals : an open access journal from MDPI · 2026Article
- Alleviating Effects of Three Heat-InactivatedAntioxidants (Basel, Switzerland) · 2026Article
- Potential opportunities and challenges of utilizing brewer's spent grain in sustainable fish feeding within the circular economy.Frontiers in physiology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Oxidative stress, a critical factor affecting the health and productivity of aquatic organisms, arises from the imbalance between reactive oxygen species (ROS) production and antioxidant defenses. In aquaculture, natural antioxidants have gained increasing attention as sustainable feed additives to mitigate oxidative damage, enhance immune responses, and improve overall growth performance. This review provides a comprehensive synthesis of the antioxidative mechanisms of key natural antioxidants, including carotenoids, polysaccharides, vitamins, polyphenols, and flavonoids. By neutralizing ROS and modulating cellular signaling pathways such as Nrf2/ARE, these compounds offer significant protective effects against oxidative damage in aquatic species. The manuscript consolidates recent advancements in antioxidant research, highlighting their practical applications in feed formulation and their role in promoting sustainability in aquaculture. This review aims to provide an integrative framework for understanding natural antioxidants' potential, guiding future research and practical implementation in aquaculture systems.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.