Evidence map›Paper›PMID 39857262›Full record

ArticleBiology2025

An Exploration of the Cellular Microenvironment of the Female Pig Urethra: Translational Insights for Urological Research.

Agustín Cartes, Caroll Stoore, María Soledad Baquedano, Christian Hidalgo, Felipe Lillo, Eduardo Landerer, Galia Ramírez-Toloza, Rodolfo Paredes

Abstract read
In one paragraph

Article in Biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Agustín CartesEscuela de Medicina Veterinaria, Facultad de Ciencias de la Vida, Universidad Andres Bello, República 239 3° Piso, Santiago 8370146, Chile.ORCID 0009-0000-4092-306X
Caroll StooreEscuela de Medicina Veterinaria, Facultad de Ciencias de la Vida, Universidad Andres Bello, República 239 3° Piso, Santiago 8370146, Chile.ORCID 0000-0001-9499-4314
María Soledad BaquedanoEscuela de Medicina Veterinaria, Facultad de Ciencias de la Vida, Universidad Andres Bello, República 239 3° Piso, Santiago 8370146, Chile.ORCID 0000-0002-9414-4480
Christian HidalgoNúcleo de Investigación en One Health (NIOH), Facultad de Medicina Veterinaria y Agronomía, Universidad de las Américas, Santiago 8370065, Chile.ORCID 0000-0002-0780-6969
Felipe LilloEscuela de Medicina Veterinaria, Facultad de Ciencias de la Vida, Universidad Andres Bello, República 239 3° Piso, Santiago 8370146, Chile.
Eduardo LandererUnidad Urología, Centro de Cirugía Robótica, Clínica Indisa, Santa María 1810, Providencia, Santiago 7520440, Chile.ORCID 0000-0002-0573-3305
Galia Ramírez-TolozaDepartamento de Medicina Preventiva Animal, Facultad de Ciencias Veterinarias y Pecuarias, Universidad de Chile, Santa Rosa 11735, La Pintana, Santiago 8820808, Chile.ORCID 0000-0001-8415-7918
Rodolfo ParedesEscuela de Medicina Veterinaria, Facultad de Ciencias de la Vida, Universidad Andres Bello, República 239 3° Piso, Santiago 8370146, Chile.ORCID 0000-0002-5909-9362

Funding

Fondef IDeA ID23I10045
6 · The paper itself

Abstract

Urinary incontinence is a widespread issue, particularly among women, with effective treatments remaining elusive. The pig, and especially the female pig, stands as a promising animal model for the study of this condition, due to its anatomical similarities to humans. The aim of this study was to explore the largely uncharted muscular structure of the female pig urethra, linking urethral muscle dysfunction to incontinence. We examined histological sections from the urethras of six sows using Hematoxylin-Eosin and Masson's trichrome staining for morphometric analysis. The statistical significance of cellular disposition was determined through analysis of variance (ANOVA), followed by a Tukey post hoc test to elucidate specific inter-group differences. Our analysis revealed segment-specific epithelial differences, including variations in cell layers, sparse acinar glands, rich vasculature, and distinct muscle fibers with diverse regional distributions. Notably, significant differences in muscular area and tissue distribution were identified between the proximal, middle, and distal segments of the urethra (

Indexed as

pig urethratranslational researchurethral anatomyurological model

Identifiers

PMID39857262
PMCPMC11761940

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.