Evidence map›Paper›PMID 39856789›Full record

ArticleKnee surgery & related research2025

Relationship between muscle activation and sagittal knee joint biomechanics in patients with patellofemoral pain syndrome: a cross-sectional study.

Byung Sun Choi, Soon Bin Kwon, Sehyeon Jeon, Myeongjun Kim, Yunseo Ku, Du Hyun Ro, Hyuk-Soo Han

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Article in Knee surgery & related research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

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6citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
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  4. Comparing kinematic and kinetic demands on the knee joint during selected physiotherapy exercises and activities of daily living.Technology and health care : official journal of the European Society for Engineering and Medicine · 2026
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5 · Who and what money

Authors and funding

7 authors.

Byung Sun ChoiDepartment of Orthopedic Surgery, Seoul National University Hospital, Seoul National University College of Medicine, 28 Yeongeon-Dong, Jongno-Gu, Seoul, 03080, Korea.ORCID https://orcid.org/0000-0002-4492-4358
Soon Bin KwonDepartment of Neurology, Columbia University Irving Medical Center, New York, NY, USA.
Sehyeon JeonSeoul National University College of Medicine, Seoul, South Korea.
Myeongjun KimSeoul National University College of Medicine, Seoul, South Korea.
Yunseo KuDepartment of Biomedical Engineering, Chungnam National University College of Medicine, Daejeon, South Korea.
Du Hyun RoDepartment of Orthopedic Surgery, Seoul National University Hospital, Seoul National University College of Medicine, 28 Yeongeon-Dong, Jongno-Gu, Seoul, 03080, Korea.
Hyuk-Soo HanDepartment of Orthopedic Surgery, Seoul National University Hospital, Seoul National University College of Medicine, 28 Yeongeon-Dong, Jongno-Gu, Seoul, 03080, Korea. oshawks7@snu.ac.kr.ORCID http://orcid.org/0000-0003-1229-8863

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatellofemoral pain syndrome (PFPS) is one of the most common conditions affecting the knee joint, yet its pathomechanics remain unclear. The aim of this study was to investigate changes in muscle activation and gait patterns and to analyze the relationship between muscle activation and kinetic gait patterns in patients with PFPS.

methodsThis study included 31 patients with PFPS and 28 healthy volunteers without any symptoms. The sagittal plane motion of the knee joint, representing primary movement of the knee joint, was evaluated to identify changes in gait patterns. Electromyography (EMG) was used to measure muscle activation of vastus medialis (VM), vastus lateralis (VL), semitendinosus (ST), and gastrocnemius (GCM) muscles during gait analysis. Biomechanical features were analyzed during the three phases of the gait cycle; weight acceptance (WA), single limb support (SLS), and swing limb advancement (SLA) (0 ~ 12%, 13 ~ 50%, and 51 ~ 100% of the gait cycle, respectively).

resultsThe average knee extension moment (KEM) during WA was lower in the patient group and no significant differences were observed in the knee flexion angle (KFA). With respect to muscle activation, the patient group showed significantly higher muscle activation of the ST muscle in all phases. As the absolute value of the moment increased, the activation of the VM, VL, and ST muscles increased more rapidly in the patient group, especially when KEM was under -1% body weight × height (Bw × Ht) or over 5% Bw × Ht.

conclusionsPatients with PFPS exhibit elevated muscle activation, particularly in response to changes in the knee extension moment, which is likely a compensatory mechanism to manage knee joint loading during gait. These results highlight altered neuromuscular adaptations in PFPS, suggesting targeted therapies may help improve functional outcomes. Level of evidence III, cross-sectional study.

Indexed as

ElectromyographyGait analysisPatellofemoral pain syndrome

Identifiers

PMID39856789
PMCPMC11763116

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.