ReviewMolecular cancer2025
The micro(nano)plastics perspective: exploring cancer development and therapy.
Review in Molecular cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Evidence on microplastic exposure and respiratory health outcomes: a systematic review.Therapeutic advances in respiratory diseasePooled it
- Micro- and Nanoplastics in the Human Exposome: Environmental Pathways, Kidney Toxicity, and Implications for Public Health Risk Assessment.International journal of molecular sciences · 2026Review
- Micro- and Nanoplastics as Environmental Stressors: Mechanistic Links Among Gut Dysbiosis, Inflammation, and Systemic Health Effects.Journal of xenobiotics · 2026Review
- Microplastics and Nanoplastics in the Human Diet: Sources of Exposure, Bioavailability, Toxicokinetics, and Systemic Health Effects.Molecules (Basel, Switzerland) · 2026Review
- Inhaled Micro- and Nanoplastics as Environmental Modifiers of Lung Carcinogenesis: Mechanistic Insights and Evidence Synthesis.Journal of xenobiotics · 2026Review
- Micro- and nanoplastic exposure and cancer: current evidence, mechanistic pathways, and translational challenges.Translational cancer research · 2026Review
- Applications of Stem Cells and Modern Toxicological Analytical Methods in the Toxicity of Microplastics.Toxics · 2026Review
- Dietary microplastic exposure and lip-oral cavity cancer: a global ecological analysis with pre-specified spatial econometric sensitivity.Scientific reports · 2026Article
- Microplastics as both a driver of genitourinary cancers and a deliverer of treatments.Communications medicine · 2026Review
- Respiratory risks of microplastics and nanoplastics: Where? What? How?Innovation (Cambridge (Mass.)) · 2026Review
- Emerging evidence on micro- and nanoplastics carcinogenicity: mechanisms, models, and signaling networks.Molecular cancer · 2026Review
- Micro and nanoplastics in dentistry: emerging sources, health implications, and mitigation pathways: a narrative review.The Saudi dental journal · 2026Review
- Polystyrene Microplastics Exposure Aggravates Clear Cell Renal Cell Carcinoma Progression via the NF-κB and TGF-β Signaling Pathways.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Protective effects of multi-strain probiotics against polystyrene nanoplastic-induced parotid gland toxicity: role of NRF2/HO-1 and NF-κB pathways.Frontiers in pharmacology · 2026Article
- Plasticizers and prostate cancer: unraveling the link through network toxicology and machine learning.Frontiers in oncology · 2026Article
- Environmental co-exposure to microplastics and phenol may influence redox signaling and tumor microenvironment dynamics.Journal of Cancer · 2026Review
- Microplastics in food production systems: Sources, exposure pathways, and gastrointestinal health effects.Current research in food science · 2026Review
- Dental composite-resin materials and oral-systemic health: clinical toxicology insights.Frontiers in public health · 2026Review
- Microplastic induced cascades of multiple cell death pathways: inflammation, immune imbalance, and cancer susceptibility.Frontiers in public health · 2026Review
- Ferroptosis inhibition via the ROS-GPX4 axis drives microplastic-induced malignant progression of nasopharyngeal carcinoma.Journal of translational medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Microplastics, as an emerging environmental pollutant, have received widespread attention for their potential impact on ecosystems and human health. Microplastics are defined as plastic particles less than 5 millimeters in diameter and can be categorized as primary and secondary microplastics. Primary microplastics usually originate directly from industrial production, while secondary microplastics are formed by the degradation of larger plastic items. Microplastics are capable of triggering cytotoxicity and chronic inflammation, and may promote cancer through mechanisms such as pro-inflammatory responses, oxidative stress and endocrine disruption. In addition, improved microplastics bring new perspectives to cancer therapy, and studies of microplastics as drug carriers are underway, showing potential for high targeting and bioavailability. Although current studies suggest an association between microplastics and certain cancers (e.g., lung, liver, and breast cancers), the long-term effects and specific mechanisms still need to be studied. This review aimed at exploring the carcinogenicity of microplastics and their promising applications in cancer therapy provides important directions for future research and emphasizes the need for multidisciplinary collaboration to address this global health challenge.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.