Evidence map›Paper›PMID 39856646›Full record

ArticleBMC pregnancy and childbirth2025

Trait mindfulness in early pregnancy and adverse perinatal outcomes: a prospective cohort study.

Audra C Fain, Tess E K Cersonsky, Margaret H Bublitz, Adam K Lewkowitz, Erika F Werner, Emily S Miller, Nina K Ayala

Abstract read
In one paragraph

Article in BMC pregnancy and childbirth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Audra C FainDepartment of Obstetrics and Gynecology, David Geffen School of Medicine UCLA, 10833 Le Conte Ave, Los Angeles, CA, CHS B2-049, USA. afain@mednet.ucla.edu.
Tess E K CersonskyDepartment of Obstetrics and Gynecology, Icahn School of Medicine Mount Sinai, New York, NY, USA.
Margaret H BublitzDepartment of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, RI, USA.
Adam K LewkowitzDivision of Maternal Fetal Medicine, Women and Infants Hospital of Rhode Island, Providence, RI, USA.
Erika F WernerDepartment of Obstetrics and Gynecology, Tufts University School of Medicine, Boston, MA, USA.
Emily S MillerDivision of Maternal Fetal Medicine, Women and Infants Hospital of Rhode Island, Providence, RI, USA.
Nina K AyalaDivision of Maternal Fetal Medicine, Women and Infants Hospital of Rhode Island, Providence, RI, USA.

Funding

Project 3: Isolating food insecurity to understand childhood health outcomes and biological mechanisms of riskP20GM139767 · NIGMS · MIRIAM HOSPITAL · PI KayLoni L. Olson · 2021 to 2026
$14.6M
NIGMS NIH HHS P20 GM139767
6 · The paper itself

Abstract

backgroundMindfulness centered therapy has been shown to improve perinatal mental health outcomes. There is emerging evidence that mindfulness training (MT) can also be harnessed to improve somatic outcomes. Yet, little is known about which perinatal populations might benefit the most from mindfulness training interventions. We aimed to evaluate the association between trait mindfulness and adverse pregnancy outcomes.

methodsThis is a planned secondary analysis of a prospective cohort study of nulliparous participants recruited between May 2019 and February 2022 from a single, high volume tertiary care center. Participants completed the validated Mindfulness and Attentive Awareness Scale prior to 20 weeks gestation. Trained research staff abstracted pregnancy and delivery data. The primary outcome was unplanned cesarean delivery (CD). Secondary outcomes included gestational diabetes, hypertensive disorders of pregnancy and a neonatal morbidity composite. We examined outcomes by mindfulness quartile (Q), adjusting for covariates determined a priori.

resultsOf the 281 participants with full outcome data, 47.9% experienced one or more of the adverse perinatal outcomes and the median trait mindfulness score was 4.6 (IQR 3.9-5.3). After adjusting for potential confounders, there were significantly lower rates of CD rates in those in Q2 and Q3 compared to Q4 (adjusted odds ratio [aOR] Q2 0.42, 95% confidence interval [CI] 0.20 - 0.87, Q3 aOR 0.23, 95% CI 0.10-0.51). There were no differences in rates of gestational diabetes, hypertension or composite neonatal outcomes by trait mindfulness quartile.

conclusionsIn this prospective cohort of nulliparous people, those with trait mindfulness in the 2nd and 3rd quartiles had lower rates of CD. Given prior literature suggesting active MT decreases adverse outcomes, there may be a component of the active practice of mindfulness, rather than trait mindfulness levels, associated with improved outcomes.

Indexed as

MindfulnessPregnancy ComplicationsPregnancy OutcomeAdultCesarean SectionDiabetes, GestationalFemaleHumansInfant, NewbornPregnancyProspective StudiesAdverse perinatal outcomesMaternal morbidityPregnancyTrait mindfulness

Identifiers

PMID39856646
PMCPMC11760720

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.