Evidence map›Paper›PMID 39856612›Full record

ArticleBMC public health2025

The association of lifestyle with cardiovascular and all-cause mortality based on machine learning: a prospective study from the NHANES.

Xinghong Guo, Mingze Ma, Lipei Zhao, Jian Wu, Yan Lin, Fengyi Fei, Clifford Silver Tarimo, Saiyi Wang, Jingyi Zhang, Xinya Cheng and 1 more

Abstract read
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xinghong Guo *Department of Health Management of Public Health, College of Public Health, Zhengzhou University, 100 Kexue Road, Gaoxin district, Zhengzhou, 450001, Henan, China.
Mingze Ma *Department of Health Management of Public Health, College of Public Health, Zhengzhou University, 100 Kexue Road, Gaoxin district, Zhengzhou, 450001, Henan, China.
Lipei Zhao *Department of Health Management of Public Health, College of Public Health, Zhengzhou University, 100 Kexue Road, Gaoxin district, Zhengzhou, 450001, Henan, China.
Jian WuDepartment of Health Management of Public Health, College of Public Health, Zhengzhou University, 100 Kexue Road, Gaoxin district, Zhengzhou, 450001, Henan, China.
Yan LinDepartment of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, No.100 Science Avenue, Zhengzhou, Henan, 450001, China.
Fengyi FeiDepartment of Health Management of Public Health, College of Public Health, Zhengzhou University, 100 Kexue Road, Gaoxin district, Zhengzhou, 450001, Henan, China.
Clifford Silver TarimoDepartment of Health Management of Public Health, College of Public Health, Zhengzhou University, 100 Kexue Road, Gaoxin district, Zhengzhou, 450001, Henan, China.
Saiyi WangDepartment of Health Management of Public Health, College of Public Health, Zhengzhou University, 100 Kexue Road, Gaoxin district, Zhengzhou, 450001, Henan, China.
Jingyi ZhangDepartment of Health Management of Public Health, College of Public Health, Zhengzhou University, 100 Kexue Road, Gaoxin district, Zhengzhou, 450001, Henan, China.
Xinya ChengFaculty of Arts and Social Sciences, Hong Kong Baptist University, 224 Waterloo Road, Kowloon Tong, Hong Kong.
Beizhu YeDepartment of Health Management of Public Health, College of Public Health, Zhengzhou University, 100 Kexue Road, Gaoxin district, Zhengzhou, 450001, Henan, China. yebeizhu@zzu.edu.cn.

Funding

2024 Graduate Independent Innovation Project of Zhengzhou University 20240332Collaborative Innovation System Research on Drug Intervention&Non-drug Intervention in Proactive Health Context 20220518AHenan Zhongyuan Medical Science and Technology Innovation and Development Foundation 23YCG1006Zhengzhou University Education Reform Research and Practice Project 2023ZZUJGXM222
6 · The paper itself

Abstract

backgroundLifestyle and cardiovascular mortality and all-cause mortality have been exhaustively explored by traditional methods, but the advantages of machine learning (ML) over traditional methods may lead to different or more precise conclusions. The aim of this study was to evaluate the effectiveness of machine learning-based lifestyle factors in predicting cardiovascular and all-cause mortality and compare the results obtained by traditional methods.

methodA prospective cohort study was conducted using a nationally representative sample of adults aged 40 years or older, drawn from the US National Health and Nutrition Examination Survey from 2007 to 2010. The participants underwent a comprehensive in-person interview and medical laboratory examinations, and subsequently, their records were linked with the National Death Index for further analysis. Extreme gradient enhancement, random forest, support vector machine and other machine learning methods are used to build the prediction model.

resultWithin a cohort comprising 7921 participants, spanning an average follow-up duration of 9.75 years, a total of 1911 deaths, including 585 cardiovascular-related deaths, were recorded. The model predicted mortality with an area under the receiver operating characteristic curve (AUC) of 0.862 and 0.836. Stratifying participants into distinct risk groups based on ML scores proved effective. All lifestyle behaviors were associated with a reduced risk of all-cause and cardiovascular mortality. As age increases, the effects of dietary scores and sedentary time on mortality risk become more pronounced, while the influence of physical activity tends to diminish.

conclusionWe develop a ML model based on lifestyle behaviors to predict all-cause and cardiovascular mortality. The developed model offers valuable insights for the assessment of individual lifestyle-related risks. It applies to individuals, healthcare professionals, and policymakers to make informed decisions.

Indexed as

Cardiovascular DiseasesLife StyleMachine LearningMortalityAdultAgedCause of DeathFemaleHumansMaleMiddle AgedNutrition SurveysProspective StudiesRisk AssessmentUnited StatesAll-cause mortalityCardiovascular mortalityLifestyle behaviorMachine learningMortality predictionRisk stratification

Identifiers

PMID39856612
PMCPMC11763113

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.