ArticleBMC psychiatry2025
Functional and structural connectivity of the subregions of the amygdala in ADHD children with or without ODD.
Article in BMC psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Neurological and biological correlations of ODD with ADHD in children and adolescents: a systematic review.BMC psychology · 2026Pooled it
- Social Dysfunction in ADHD Children Associated With Increased Amygdala Functional Connectivity Instability: A Static and Dynamic Functional Connectivity Study.CNS neuroscience & therapeutics · 2026Article
- The relationship of sensory processing with ADHD and its co-occurring behavioural symptoms based on both undirected and directed network analysis.BMC psychiatry · 2025Article
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Authors and funding
12 authors.
Funding
Abstract
objectivesThe current study aimed to investigate the structural and functional connectivity of the subregions of the amygdala in children with Attention Deficit/Hyperactivity Disorder (ADHD) only or comorbid with Oppositional Defiant Disorder (ODD).
methodsA total of 354 children with ADHD-only, 161 children with ADHD and ODD (ADHD + ODD), and 100 healthy controls were enrolled. The Child Behavior Checklist (CBCL) and the Behavior Rating Inventory of Executive Function (BRIEF) were filled out by caregivers. Analysis of covariance (ANCOVA) was performed to test group-wise differences in these behavioral measures. A subsample comprising 209 participants underwent a resting-state functional MRI scan and a diffusion-weighted imaging (DWI) scan. Functional connectivity and structural connectivity were calculated using bilateral subregions of the Amygdala as seeds. Between-group voxel-wise comparisons were conducted.
resultsThe ADHD + ODD group had more anxious/depressed moods, more delinquent and aggressive behaviors, more emotional control problems, and more inhibition deficits than the ADHD-only group (all P
conclusionsAltered structural and functional connectivity of the subregions of the amygdala in children with ADHD compared with their healthy counterparts were respectively associated with ADHD-related behavioral and emotional problems. CLINICAL TRIAL NUMBER: not applicable.
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