Evidence map›Paper›PMID 39856418›Full record

ArticleArchives of orthopaedic and trauma surgery2025

Autologous minced cartilage implantation in osteochondral lesions of the talus-does fibrin make the difference?

Jan Kühle, Ferdinand C Wagner, Samuel Beck, Lukas Klein, Lisa Bode, Kaywan Izadpanah, Hagen Schmal, Nils Mühlenfeld

Abstract read
In one paragraph

Article in Archives of orthopaedic and trauma surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jan KühleUniversity Medical Center Freiburg, Freiburg, Germany.
Ferdinand C WagnerUniversity Medical Center Freiburg, Freiburg, Germany.
Samuel BeckUniversity Medical Center Freiburg, Freiburg, Germany.
Lukas KleinUniversity Medical Center Freiburg, Freiburg, Germany.
Lisa BodeUniversity Medical Center Freiburg, Freiburg, Germany.
Kaywan IzadpanahUniversity Medical Center Freiburg, Freiburg, Germany.
Hagen SchmalUniversity Medical Center Freiburg, Freiburg, Germany.
Nils MühlenfeldUniversity Medical Center Freiburg, Freiburg, Germany. nils.muehlenfeld@uniklinik-freiburg.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionImplantation of minced cartilage is a one-step-procedure that leads to satisfactory results in osteochondral defects. MATERIAL AND

methodsA retrospective review was performed on a consecutive cohort of patients that received minced cartilage with fibrin (MCF), minced cartilage with membrane and fibrin (MCMF) and minced cartilage with the "AutoCart"-procedure (MCAC) between January 2019 and December 2023. Radiological outcome parameters were evaluated via Magnet-Resonance-Tomography (MRI) within one year using Ankle-Osteoarthritis-Scoring-System (AOSS).

resultsFinal data included 25 patients: 13 women and 12 men with a mean age of 28.2 years ± 10.9(range:18-51). Mean defect size was 103.6mm

conclusionsAutologous minced cartilage implantation seems to be sufficient as a viable, one-step treatment for osteochondral lesions of the talus. It leads to low complication rates and excellent AOSS values within a 12-month period whereas the application of fibrin as the last fixation layer seems to be advisory, which demands further investigation.

Indexed as

CartilageOsteochondritisOsteochondrosisTalusAdolescentAdultFemaleFibrinHumansMaleRetrospective StudiesTransplantation, AutologousYoung AdultFibrinAnkle surgeryCartilage repairMinced cartilageOsteochondral lesion

Identifiers

PMID39856418
PMCPMC11761507

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