Evidence map›Paper›PMID 39856244›Full record

Observational studyInternational journal of obesity (2005)2025

Diurnal timing of physical activity in relation to obesity and diabetes in the German National Cohort (NAKO).

Michael J Stein, Andrea Weber, Fabian Bamberg, Hansjörg Baurecht, Klaus Berger, Patricia Bohmann, Hermann Brenner, Julian Brummer, Marcus Dörr, Beate Fischer and 24 more

Abstract readObservational Study
In one paragraph

Observational study in International journal of obesity (2005), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

34 authors.

Michael J SteinDepartment of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany. michael.stein@ukr.de.ORCID 0000-0002-1120-1751
Andrea WeberDepartment of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany.
Fabian BambergDepartment of Diagnostic and Interventional Radiology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Hansjörg BaurechtDepartment of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany.ORCID 0000-0002-9265-5594
Klaus BergerInstitute of Epidemiology and Social Medicine, University of Münster, Münster, Germany.
Patricia BohmannDepartment of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany.
Hermann BrennerDivision of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.ORCID 0000-0002-6129-1572
Julian BrummerDivision of Physical Activity, Prevention and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Marcus DörrDepartment of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany.
Beate FischerDepartment of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany.
Sylvia GastellDepartment of Molecular Metabolism and Precision Nutrition, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany.
Karin Halina GreiserDivision of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.ORCID 0000-0003-3213-8285
Volker HarthInstitute for Occupational and Maritime Medicine (ZfAM), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Antje HebestreitDepartment of Epidemiological Methods and Etiological Research, Leibniz Institute for Prevention Research and Epidemiology - BIPS, Bremen, Germany.ORCID 0000-0001-7354-5958
Jana-Kristin HeiseDepartment for Epidemiology, Helmholtz Centre for Infection Research (HZI), Hannover, Germany.
Florian HerbolsheimerDivision of Physical Activity, Prevention and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Till IttermannDepartment SHIP clinical epidemiological research, Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.
André KarchInstitute of Epidemiology and Social Medicine, University of Münster, Münster, Germany.
Thomas KeilInstitute of Social Medicine, Epidemiology and Health Economics, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Alexander KluttigInstitute of Medical Epidemiology, Biometrics, and Informatics, Medical Faculty of the Martin-Luther-University Halle-Wittenberg, Halle (Saale), Germany.
Lilian KristInstitute of Social Medicine, Epidemiology and Health Economics, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Karin B MichelsInstitute for Prevention and Cancer Epidemiology, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.
Rafael MikolajczykInstitute of Medical Epidemiology, Biometrics, and Informatics, Medical Faculty of the Martin-Luther-University Halle-Wittenberg, Halle (Saale), Germany.
Matthias NauckGerman Centre for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald, Germany.ORCID 0000-0002-6678-7964
Katharina NimptschMax-Delbrueck-Center for Molecular Medicine in the Helmholtz Association (MDC), Molecular Epidemiology Research Group, Berlin, Germany.
Nadia ObiInstitute for Occupational and Maritime Medicine (ZfAM), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Tobias PischonMax-Delbrueck-Center for Molecular Medicine in the Helmholtz Association (MDC), Molecular Epidemiology Research Group, Berlin, Germany.ORCID 0000-0003-1568-767X
Olga Pivovarova-RamichDepartment of Molecular Metabolism and Precision Nutrition, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany.
Tamara SchikowskiDepartment of Epidemiology, IUF-Leibniz Research Institute for Environmental Medicine, Düsseldorf, Germany.
Börge SchmidtInstitute for Medical Informatics, Biometry and Epidemiology, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Matthias B SchulzeGerman Center for Diabetes Research (DZD), Neuherberg, Germany.ORCID 0000-0002-0830-5277
Karen SteindorfDivision of Physical Activity, Prevention and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Stephanie ZyllaInstitute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany.ORCID 0000-0001-7417-4407
Michael F LeitzmannDepartment of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPhysical activity supports weight regulation and metabolic health, but its timing in relation to obesity and diabetes remains unclear. We aimed to assess the diurnal timing of physical activity and its association with obesity and diabetes.

methodsWe cross-sectionally analyzed hip-worn accelerometry data from 61,116 participants aged 20-75 in the German National Cohort between 2015 and 2019. We divided physical activity into sex- and age-standardized quartiles of total morning (06:00-11:59), afternoon (12:00-17:59), evening (18:00-23:59), and nighttime (00:00-06:00) physical activity. Using multivariable logistic regression, we estimated associations of physical activity timing with obesity (BMI ≥ 30.0 kg/m

resultsHigh afternoon (top vs. bottom quartile, OR: 0.36, 95% CI: 0.33-0.38) and evening physical activity (OR: 0.45, 95% CI: 0.42-0.48) showed lower obesity odds than high morning activity (OR: 0.71, 95% CI: 0.66-0.76), whereas nighttime activity increased obesity odds (OR: 1.58, 95% CI: 1.48-1.68). Associations were similar for diabetes, with the lowest odds for afternoon (OR: 0.47, 95% CI: 0.42-0.53), followed by evening (OR: 0.56, 95% CI: 0.50-0.62) and morning activity (OR: 0.80, 95% CI: 0.71-0.89), and higher odds for nighttime activity (OR: 1.43, 95% CI: 1.29-1.58). Findings were not modified by employment status, night shift work, and sleep duration.

conclusionsOur cross-sectional findings require longitudinal corroboration but suggest afternoon and evening activity provide greater metabolic health benefits than morning activity, while nighttime activity is discouraged.

Indexed as

Circadian RhythmDiabetes MellitusExerciseObesityAccelerometryAdultAgedCohort StudiesCross-Sectional StudiesFemaleGermanyHumansMaleMiddle AgedTime FactorsYoung Adult

Identifiers

PMID39856244
PMCPMC12095084

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.