Evidence map›Paper›PMID 39856201›Full record

ArticleInternational orthopaedics2025

Influence of parkinson's disease on complications and revisions in total hip and knee arthroplasty: insights from a matched pair analysis.

Dominik Emanuel Holzapfel, Tobias Kappenschneider, Marie Farina Schuster, Stefano Pagano, Fady Azar, Sabrina Holzapfel, Matthias Meyer

Abstract read
In one paragraph

Article in International orthopaedics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dominik Emanuel HolzapfelDepartment of Orthopaedic Surgery, Regensburg University Medical Center, Bad Abbach, Germany. dominik.holzapfel@klinik.uni-regensburg.de.ORCID 0000-0002-0236-695X
Tobias KappenschneiderDepartment of Orthopaedic Surgery, Regensburg University Medical Center, Bad Abbach, Germany.
Marie Farina SchusterDepartment of Orthopaedic Surgery, Regensburg University Medical Center, Bad Abbach, Germany.
Stefano PaganoDepartment of Orthopaedic Surgery, Regensburg University Medical Center, Bad Abbach, Germany.
Fady AzarDepartment of Orthopaedic Surgery, Regensburg University Medical Center, Bad Abbach, Germany.
Sabrina HolzapfelDepartment of Neonatology, University Children´S Hospital Regensburg, Hospital St. Hedwig of the Order of St John, University of Regensburg, Regensburg, Germany.
Matthias MeyerDepartment of Orthopaedic Surgery and Traumatology, Altmühltal Nature Park Clinics, Eichstätt, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe outcome of elective total joint arthroplasty (TJA) in patients with Parkinson's disease (PD) is controversial due to the concomitant risk profile. This study investigated postoperative complications and revision rates following total hip (THA) and knee arthroplasty (TKA) in patients with PD.

methodsNinety-six patients with PD undergoing THA or TKA were matched 1:1 with non-PD patients using propensity score matching for age, sex and comorbidity (Charlson Comorbidity index, CCI). Rates of revisions, medical and surgical complications were compared. Univariate and multivariate regression analyses were calculated.

resultsPD patients exhibited higher rates of revision-surgeries within 90 days (13.5% vs. 5.2%; p = 0.048), medical complications (68.8% vs. 43.8%; p < 0.001) and surgical complications (40.6% vs. 21.9%; p = 0.005). Multivariate regression analysis confirmed PD as a significant risk factor for complications and long-term revision-surgeries.

conclusionPD increases the risk of adverse outcomes following THA and TKA. Improvements in pre-operative planning and post-operative care are critical to the improvement of outcomes in this vulnerable population.

Indexed as

Arthroplasty, Replacement, HipArthroplasty, Replacement, KneeParkinson DiseasePostoperative ComplicationsAgedAged, 80 and overFemaleHumansMaleMatched-Pair AnalysisMiddle AgedPropensity ScoreReoperationRetrospective StudiesRisk FactorsParkinson’s diseasePostoperative complicationsRevision surgeryTHATJATKA

Identifiers

PMID39856201
PMCPMC11889065

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.