Evidence map›Paper›PMID 39856165›Full record

Trial reportScientific reports2025

Effect of a virtual walking and exercise-based intervention on muscle strength and activation in people with incomplete spinal cord injury.

Sara Mollà-Casanova, Elena Muñoz-Gómez, Noemí Moreno-Segura, Marta Inglés, Marta Aguilar-Rodríguez, Núria Sempere-Rubio, Pilar Serra-Añó

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04809987 (Evaluation of Effectiveness of Virtual Gait System Intervention in Motor Function, Tone and Sensibility, in People With Incomplete Spinal Cord Injury.), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04809987 nacompletednot on this map

Evaluation of Effectiveness of Virtual Gait System Intervention in Motor Function, Tone and Sensibility, in People With Incomplete Spinal Cord Injury.

TypeinterventionalSponsorUniversity of ValenciaRan2021 to 2025Enrolled38ConditionsIncomplete Spinal Cord InjuryArmsVirtual Gait, Physical Exercise, Documental projection
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sara Mollà-CasanovaUBIC Research Group, Department of Physiotherapy, Faculty of Physiotherapy, University of Valencia, Gascó Oliag, 5, Valencia, Spain.
Elena Muñoz-GómezUBIC Research Group, Department of Physiotherapy, Faculty of Physiotherapy, University of Valencia, Gascó Oliag, 5, Valencia, Spain.
Noemí Moreno-SeguraUBIC Research Group, Department of Physiotherapy, Faculty of Physiotherapy, University of Valencia, Gascó Oliag, 5, Valencia, Spain.
Marta InglésUBIC Research Group, Department of Physiotherapy, Faculty of Physiotherapy, University of Valencia, Gascó Oliag, 5, Valencia, Spain.
Marta Aguilar-RodríguezUBIC Research Group, Department of Physiotherapy, Faculty of Physiotherapy, University of Valencia, Gascó Oliag, 5, Valencia, Spain.
Núria Sempere-RubioUBIC Research Group, Department of Physiotherapy, Faculty of Physiotherapy, University of Valencia, Gascó Oliag, 5, Valencia, Spain. nuria.sempere@uv.es.
Pilar Serra-AñóUBIC Research Group, Department of Physiotherapy, Faculty of Physiotherapy, University of Valencia, Gascó Oliag, 5, Valencia, Spain.

Funding

Conselleria de Innovación, Universidades, Ciencia y Sociedad Digital, Generalitat Valenciana CIAICO/2021/215Spanish Government PID2021-125694OB-I00Universitat de València INV19-01-13-07
6 · The paper itself

Abstract

This study aims to assess the effect of combining virtual walking (VW) therapy with a physical exercise (PE) program compared to PE alone on lower limb strength and muscle activation in people with incomplete spinal cord injury (iSCI). 38 participants performed 3 sessions/week during 6 weeks of Experimental Intervention (EI): VW and PE; or Control intervention (CI): Placebo-VW and PE. Strength and muscle activation of main lower limb muscles were assessed. EI group exhibited a general strength increase after intervention (T2), (16.31-34.72 N), and maintained this improvement up to 1-month-follow-up (T3) for hip abduction and extension movements. The CI group only showed improvements in hip abduction and extension movements (18.34 (7.13) N and 19.98 (9.60) N, respectively). EI group also exhibited an increase of activation in all agonistic muscles in T2 (36.02-20.24 µV), except gastrocnemius. Gastrocnemius and rectus femoris activation as antagonistic decreased during dorsal flexion (- 14.28 (5.61) µV) and hip extension (- 14.78 [6.11] µV), respectively. CI group only showed an activation increase of agonistic muscles of hip abduction and extension (22.16 (9.80) µV and 28.82 (9.14) µV, respectively), without changes in antagonistic activation. VW could enhance the PE effects regarding muscle strength and activation in people with iSCI.Registration number: NCT04809987.

Indexed as

Exercise TherapyMuscle StrengthSpinal Cord InjuriesWalkingAdultFemaleHumansLower ExtremityMaleMiddle AgedMuscle, SkeletalYoung AdultMuscle activationPhysical exerciseSpinal cord injuryVirtual walking

Identifiers

PMID39856165
PMCPMC11761486

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.