Evidence map›Paper›PMID 39856095›Full record

ArticleNPJ primary care respiratory medicine2025

The availability of drugs for stable COPD treatment in China: a cross-sectional survey.

Dongru Du, Xueru Hu, Qiunan Zuo, Dan Xu, Tao Zhu, Tao Fan, Jiao Yang, Weiguo Xu, Hailong Wei, Kangzhuo Baima and 6 more

Abstract read
In one paragraph

Article in NPJ primary care respiratory medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Dongru Du *Department of Pulmonary and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, 610041, China.
Xueru Hu *Department of Pulmonary and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, 610041, China.
Qiunan Zuo *Respiratory Ward, Department of Geriatrics, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, 611731, China.
Dan XuDepartment of Pulmonary and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, 610041, China.
Tao ZhuDepartment of Pulmonary and Critical Care Medicine, Suining Central Hospital, Suining, 629099, China.
Tao FanDepartment of Integrated Traditional Chinese and Western Medicine, West China Hospital, Sichuan University, Chengdu, 610041, China.
Jiao YangDepartment of Pulmonary and Critical Care Medicine, Hunan University of Medicine General Hospital, Huaihua, 418000, China.
Weiguo XuDepartment of Pulmonary and Critical Care Medicine, Mianyang Central Hospital, Mianyang, 621000, China.
Hailong WeiDepartment of Pulmonary and Critical Care Medicine, The People's Hospital of Leshan, Leshan, 614000, China.
Kangzhuo BaimaSchool of Medicine, Tibet University, Lhasa, 850000, China.
Ying ZhangDepartment of Pulmonary and Critical Care Medicine, Daping Hospital, Army Medical Center, Chongqing, 400042, China.
Yanhui GuDepartment of Respiratory and Critical Care Medicine, Affiliated Hospital of Zunyi Medical University, Zunyi, 563099, China.
Lei ChenDepartment of Pulmonary and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, 610041, China.
Fengming LuoDepartment of Pulmonary and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, 610041, China. fengmingluo@outlook.com.
Yongchun ShenDepartment of Pulmonary and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, 610041, China. shen_yongchun@126.com.
Fuqiang WenDepartment of Pulmonary and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, 610041, China.

Funding

National Natural Science Foundation of China 82170046, 31871157, and 81830001
6 · The paper itself

Abstract

This survey aimed to investigate the availability of drugs for stable chronic obstructive pulmonary disease (COPD) treatment in Chinese hospitals and to determine whether drug availability significantly varied among hospitals with different characteristics. A well-constructed questionnaire was designed according to the Chinese Guidelines for the Diagnosis and Management of COPD (revised version 2021). Both inhaled drugs (monotherapy, double therapy and triple therapy) and oral drugs (expectorants, theophylline, antibiotics, and bacterial lysates) were included in this survey. Doctors from different hospitals completed the survey via WeChat. The availability of each category and kind of drug was analyzed based on final valid responses. Subgroup analyses were also conducted to reveal drug availability in hospitals with different characteristics. A total of 1018 hospitals with different characteristics were enrolled in this survey, with 53.73% of which establishing independent respiratory departments. Insufficient supply of COPD-related drugs was observed, with only short-acting β2 agonists (80.6%), expectorants (88.2%) and antibiotics (84.3%) reaching 80%. Results of subgroup analyses suggested that primary hospitals were associated with poorer availability of all kinds of drugs than secondary and tertiary hospitals (all p < 0.001). Most inhaled drugs did not reach an availability of 20% in primary hospitals, except for salbutamol (59.7%), tiotropium bromide (20.0%) and beclometasone/formoterol (23.1%). Results of this survey suggested that the availability of drugs for COPD treatment in China is still an ongoing challenge for healthcare institutions. Insufficient drug supply and imbalanced drug availability among different hospitals are major barriers that warrant further improvements.

Indexed as

Bronchodilator AgentsPulmonary Disease, Chronic ObstructiveAdministration, InhalationAdrenergic beta-2 Receptor AgonistsAnti-Bacterial AgentsChinaCross-Sectional StudiesExpectorantsHospitalsHumansSurveys and QuestionnairesTheophyllineAdrenergic beta-2 Receptor AgonistsAnti-Bacterial AgentsBronchodilator AgentsExpectorantsTheophylline

Identifiers

PMID39856095
PMCPMC11760382

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.