Evidence map›Paper›PMID 39856034›Full record

ArticleNature communications2025

Network structure influences the strength of learned neural representations.

Ari E Kahn, Karol Szymula, Sophie Loman, Edda B Haggerty, Nathaniel Nyema, Geoffrey K Aguirre, Dani S Bassett

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Trial-by-trial learning of successor representations in human behavior.bioRxiv : the preprint server for biology · 2025
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Ari E KahnPrinceton Neuroscience Institute and Department of Psychology, Princeton University, Princeton, NJ, 08540, USA.ORCID http://orcid.org/0000-0002-2127-0507
Karol SzymulaMedical Scientist Training Program, University of Rochester School of Medicine and Dentistry, Rochester, NY, 14642, USA.ORCID http://orcid.org/0000-0003-1822-0688
Sophie LomanDepartment of Bioengineering, School of Engineering & Applied Science, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Edda B HaggertyDepartment of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.ORCID http://orcid.org/0000-0003-0597-7956
Nathaniel NyemaDepartment of Bioengineering, School of Engineering & Applied Science, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Geoffrey K AguirreDepartment of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Dani S BassettDepartment of Bioengineering, School of Engineering & Applied Science, University of Pennsylvania, Philadelphia, PA, 19104, USA. dsb@seas.upenn.edu.ORCID http://orcid.org/0000-0002-6183-4493

Funding

Scientific TransparencyP30EY001583 · NEI · UNIVERSITY OF PENNSYLVANIA · PI Qi N Cui · 1985 to 2026
$19.5M
Development and validation of a computational model of higher-order statistical learning on graphs in humansR21MH124121 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI BASSETT, DANIELLE SMITH · 2020 to 2020
$431k
NEI NIH HHS P30 EY001583NIMH NIH HHS R21 MH124121
6 · The paper itself

Abstract

From sequences of discrete events, humans build mental models of their world. Referred to as graph learning, the process produces a model encoding the graph of event-to-event transition probabilities. Recent evidence suggests that some networks are easier to learn than others, but the neural underpinnings of this effect remain unknown. Here we use fMRI to show that even over short timescales the network structure of a temporal sequence of stimuli determines the fidelity of event representations as well as the dimensionality of the space in which those representations are encoded: when the graph was modular as opposed to lattice-like, BOLD representations in visual areas better predicted trial identity and displayed higher intrinsic dimensionality. Broadly, our study shows that network context influences the strength of learned neural representations, motivating future work in the design, optimization, and adaptation of network contexts for distinct types of learning.

Indexed as

BrainLearningNerve NetAdultBrain MappingFemaleHumansMagnetic Resonance ImagingMaleModels, NeurologicalVisual CortexYoung Adult

Identifiers

PMID39856034
PMCPMC11759951

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.