Evidence map›Paper›PMID 39855676›Full record

ArticleJournal of neurointerventional surgery2025

Tenzing Assisted Delivery of Aspiration (TADA) technique for thrombectomy of medium vessel occlusions using the Freeclimb 54 catheter: multicenter experience.

Fabio Settecase, Ajit S Puri, Shane Sh Lee, Rajkamal S Khangura, Ronald F Budzik, Peter J Pema, Thymur Chaudury, Matthew J Page, Ben J McGuinness, Marco Colasurdo and 12 more

Abstract readMulticenter Study
In one paragraph

Article in Journal of neurointerventional surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Overcoming the black box of aspiration thrombectomy in acute ischemic stroke: An early clinical experience of using contrast injections to understand clot-catheter interactions.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Fabio SettecaseNeurointerventional Surgery, Sutter Health California Pacific Medical Center, San Francisco, California, USA fsettecase@gmail.com.ORCID http://orcid.org/0000-0002-5829-3163
Ajit S PuriInterventional Neuroradiology, UMass Memorial Health, Worcester, Massachusetts, USA.
Shane Sh LeeRadiology, Auckland City Hospital, Auckland, New Zealand.
Rajkamal S KhanguraNeurointerventional Radiology, Sutter Health Sacramento Medical Center, Sacramento, California, USA.
Ronald F BudzikNeuroradiology, OhioHealth, Columbus, Ohio, USA.
Peter J PemaNeuroradiology, OhioHealth, Columbus, Ohio, USA.
Thymur ChauduryNeurointerventional Radiology, Sutter Health Sacramento Medical Center, Sacramento, California, USA.
Matthew J PageRadiology, Auckland City Hospital, Auckland, New Zealand.
Ben J McGuinnessRadiology, Auckland City Hospital, Auckland, New Zealand.ORCID http://orcid.org/0000-0001-6685-4154
Marco ColasurdoDotter Interventional Institute, Oregon Health and Science University, Portland, Oregon, USA.
Daniel A TonettiNeurosurgery, Cooper University Health Care, Camden, New Jersey, USA.
Jonathan A GrossbergNeurosurgery and Radiology, Emory University School of Medicine, Atlanta, Georgia, USA.ORCID http://orcid.org/0000-0002-1152-8826
Jasmeet SinghInterventional Neuroradiology, UMass Memorial Health, Worcester, Massachusetts, USA.
Anna Luisa KuhnInterventional Neuroradiology, UMass Memorial Health, Worcester, Massachusetts, USA.
Matthew D AlexanderNeurointerventional Radiology, Sutter Health Sacramento Medical Center, Sacramento, California, USA.
Bahram VarjavandNeurointerventional Radiology, Sutter Health Sacramento Medical Center, Sacramento, California, USA.
Ryan A PriestDotter Interventional Institute, Oregon Health and Science University, Portland, Oregon, USA.
JaeHyun KimNeurointerventional Surgery, Sutter Health California Pacific Medical Center, San Francisco, California, USA.
Blaise W BaxterNeurointerventional Surgery, Sutter Health California Pacific Medical Center, San Francisco, California, USA.
Warren T KimNeurointerventional Surgery, Sutter Health California Pacific Medical Center, San Francisco, California, USA.
Joey D EnglishNeurointerventional Surgery, Sutter Health California Pacific Medical Center, San Francisco, California, USA.
James CaldwellRadiology, Auckland City Hospital, Auckland, New Zealand.ORCID http://orcid.org/0000-0002-2353-9901

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMedium vessel occlusions (MeVOs) account for 25-40% of acute ischemic stroke. The Tenzing 5 (Route 92 Medical, San Mateo, California, USA) and FreeClimb 54 (Route 92 Medical, San Mateo, California, USA) catheter is a novel delivery-aspiration catheter combination designed to facilitate aspiration thrombectomy (AT) of MeVOs. We report our clinical experience using the Tenzing assisted delivery of aspiration (TADA) technique with FreeClimb 54 for first-line AT of MeVO.

methodsWe retrospectively reviewed consecutive patients who underwent MeVO first-line AT using TADA with FreeClimb 54 at nine institutions in the USA and one in New Zealand.

results94 MeVOs (65 primary, 29 secondary) were treated in 92 patients: median age 71 (IQR 58-81) years; 49/92 (53%) women. FreeClimb 54 was successfully delivered by Tenzing 5 to all 94/94 MeVOs: 26 proximal M2; 44 distal M2; 5 M3; 6 A2; 4 A3; and 8 P2. Median target vessel diameter on DSA was 1.7 (IQR 1.4-1.8) mm. A leading microwire was used to advance Tenzing in 84% of cases. A stent retriever was used for additional thrombectomy passes in 6/94 (6%) patients. For a primary MeVO, final modified expanded Thrombolysis in Cerebral Infarction (meTICI) 2B-3 reperfusion was achieved in 63/65 (97%) patients, after a median of 1 (IQR 1-2) pass, with a first pass effect (FPE, meTICI 2C-3) in 43/65 (66%). Secondary MeVO FPE (eTICI 2C-3) was achieved in 20/29 (69%) patients. Tenzing 5-FreeClimb 54 related complications occurred in 2/94 (2%) patients: one perforation with asymptomatic subarachnoid hemorrhage and one embolus to new territory.

conclusionsMeVO first-line AT using the TADA technique with Tenzing 5 and FreeClimb 54 had a high FPE with a low complication rate.

Indexed as

CathetersIschemic StrokeThrombectomyAgedAged, 80 and overFemaleHumansMaleMiddle AgedRetrospective StudiesSuctionTreatment OutcomeCatheterDeviceStrokeTechniqueThrombectomy

Identifiers

PMID39855676
PMCPMC12171431

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.