Evidence map›Paper›PMID 39855622›Full record

ArticleThe Journal of pediatrics2025

The Relationship Between Hispanic Ethnicity and Outcomes for Infants Born Extremely Preterm.

Jane E Brumbaugh, Carla M Bann, Edward F Bell, Colm P Travers, Betty R Vohr, Elisabeth C McGowan, Heidi M Harmon, Waldemar A Carlo, Susan R Hintz, Andrea F Duncan and 1 more

Registry-linked trialAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00063063 (Generic Database), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00063063 recruitingnot on this map

Generic Database: A Survey of Morbidity and Mortality in Very Low Birth Weight Infants

TypeobservationalSponsorNICHD Neonatal Research NetworkRan1987 to 2030Enrolled80,000ConditionsInfant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, PrematureArmsNo Intervention
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jane E BrumbaughDepartment of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN. Electronic address: Brumbaugh.Jane@mayo.edu.
Carla M BannSocial, Statistical and Environmental Sciences Unit, RTI International, Research Triangle Park, NC.
Edward F BellDepartment of Pediatrics, University of Iowa, Iowa City, IA.
Colm P TraversDepartment of Pediatrics, University of Alabama at Birmingham, Birmingham, AL.
Betty R VohrDepartment of Pediatrics, Women & Infants Hospital of Rhode Island and Warren Albert Medical School of Brown University.
Elisabeth C McGowanDepartment of Pediatrics, Women & Infants Hospital of Rhode Island and Warren Albert Medical School of Brown University.
Heidi M HarmonDepartment of Pediatrics, University of Iowa, Iowa City, IA.
Waldemar A CarloDepartment of Pediatrics, University of Alabama at Birmingham, Birmingham, AL.
Susan R HintzDivision of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University School of Medicine and Lucile Packard Children's Hospital, Palo Alto, CA.
Andrea F DuncanDepartment of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.
Eunice Kennedy Shriver NICHD Neonatal Research Network

Funding

Neonatal Research Network Data Coordinating Center (DCC)U10HD036790 · NICHD · RESEARCH TRIANGLE INSTITUTE · PI DAS, ABHIK · 2008 to 2017
$62.3M
North Carolina Translational & Clinical Sciences Institute (NC TraCS)UL1TR001111 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, CAREY, TIMOTHY S · 2013 to 2017
$43.9M
Duke CTSA (Composite)UL1TR001117 · NCATS · DUKE UNIVERSITY · PI BOULWARE, LEIGH E, LI, JENNIFER S · 2013 to 2017
$41.3M
WORKER PROTECTION AGAINST AIRBORNE INFLUENZA - A PILOT STUDYM01RR007122 · NCRR · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI WASHBURN, LISA K · 1992 to 2010
$35.2M
Data Ctr for the Cooperative Neonatal Research NetworkU01HD036790 · NICHD · RESEARCH TRIANGLE INSTITUTE · PI DAS, ABHIK · 1998 to 2007
$21.8M
UNIVERSITY OF UTAH CENTER FOR CLINICAL AND TRANSLATIONAL SCIENCE-UL1: BPCAUL1RR025764 · NCRR · UNIVERSITY OF UTAH · PI MCCLAIN, DONALD A. · 2008 to 2011
$19.4M
University of Iowa Clinical and Translational Science ProgramUL1TR000442 · NCATS · UNIVERSITY OF IOWA · PI ROSENTHAL, GARY E · 2012 to 2013
$10.0M
USE OF OXANDROLONE TO IMPROVE FUNCTION IN CHRONIC SCIM01RR016587 · NCRR · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI LEVIS, SILVINA · 2002 to 2005
$6.8M
MULTICENTER NETWORK OF NEONATAL INTENSIVE CARE UNITSU10HD021397 · NICHD · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI DUARA, SHAHNAZ · 1991 to 2006
$6.7M
Stanford Center for Clinical and Translational Education and Research (SCCTER)UL1UL1TR000093 · NCATS · STANFORD UNIVERSITY · PI GREENBERG, HARRY BERNARD · 2012 to 2013
$6.5M
NICHD Cooperative Multicenter Neonatal Research NetworkU10HD021373 · NICHD · UNIVERSITY OF TEXAS SW MED CTR/DALLAS · PI KENNEDY, KATHLEEN A · 1991 to 2015
$6.1M
NICHD Cooperative Multicenter Neonatal Research NetworkU10HD027871 · NICHD · YALE UNIVERSITY · PI EHRENKRANZ, RICHARD A. · 1991 to 2012
$3.9M
NCATS NIH HHS UL1 TR000093NCATS NIH HHS UL1 TR000442NCATS NIH HHS UL1 TR001111NCATS NIH HHS UL1 TR001117NCRR NIH HHS M01 RR007122NCRR NIH HHS M01 RR016587NCRR NIH HHS UL1 RR025764NICHD NIH HHS U01 HD036790NICHD NIH HHS U10 HD021373NICHD NIH HHS U10 HD021397NICHD NIH HHS U10 HD027871NICHD NIH HHS U10 HD036790NICHD NIH HHS U10 HD040461NICHD NIH HHS U10 HD040498NICHD NIH HHS U10 HD040521NICHD NIH HHS U10 HD053119NICHD NIH HHS U10 HD053124NICHD NIH HHS U10 HD068278NICHD NIH HHS UG1 HD021364NICHD NIH HHS UG1 HD021385NICHD NIH HHS UG1 HD027851NICHD NIH HHS UG1 HD027853NICHD NIH HHS UG1 HD027856NICHD NIH HHS UG1 HD027880NICHD NIH HHS UG1 HD027904NICHD NIH HHS UG1 HD034216NICHD NIH HHS UG1 HD040492NICHD NIH HHS UG1 HD040689NICHD NIH HHS UG1 HD053089NICHD NIH HHS UG1 HD053109NICHD NIH HHS UG1 HD068244NICHD NIH HHS UG1 HD068263NICHD NIH HHS UG1 HD068270NICHD NIH HHS UG1 HD068284NICHD NIH HHS UG1 HD087226NICHD NIH HHS UG1 HD087229NICHD NIH HHS UG1 HD104252NICHD NIH HHS UG1 HD112093
6 · The paper itself

Abstract

objectiveTo characterize the association between maternal ethnicity and infant survival to discharge without major morbidity. STUDY

designThis is secondary analysis of a prospective cohort of infants born <27 weeks of gestation at National Institute of Child Health and Human Development Neonatal Research Network centers from 2006 through 2020. The primary outcome was survival to discharge without major morbidity (sepsis, necrotizing enterocolitis, bronchopulmonary dysplasia grade 3, intracranial hemorrhage grade ≥3, periventricular leukomalacia, and advanced retinopathy of prematurity). Outcomes were compared by ethnicity and adjusted for center, perinatal characteristics, and sociodemographic characteristics.

resultsOf 14 029 subjects, 2155 (15%) were Hispanic, 6116 (44%) non-Hispanic Black, and 5758 (41%) non-Hispanic White. Infants of Hispanic mothers had the lowest survival to discharge without major morbidity (Hispanic 523/2099 [25%], non-Hispanic Black 1701/5940 [29%], non-Hispanic White 1494/5597 [27%], P = .002). Adjusted odds of survival without major morbidity differed between Hispanic and non-Hispanic Black (adjusted odds ratio [aOR] 0.80, 95% CI 0.69-0.93), but not between Hispanic and non-Hispanic White infants (aOR 1.07, 95% CI 0.92-1.25). At 2 years, children of non-Hispanic White mothers had the lowest incidence of neurodevelopmental impairment (Hispanic 544/1235 [44%], non-Hispanic Black 1574/3482 [45%], and non-Hispanic White 1004/3182 [32%], P < .001). Odds of impairment were greater for Hispanic than non-Hispanic White children (aOR 1.25, 95% CI 1.05-1.48) but did not differ between Hispanic and non-Hispanic Black children (aOR 0.88, 95% CI 0.74-1.04).

conclusionsIn a multicenter cohort, infants of Hispanic mothers had lower odds of survival to discharge without major morbidity than infants of non-Hispanic Black mothers and similar odds of survival without major morbidity as infants of non-Hispanic White mothers. CLINICALTRIALS: GOV ID: Generic Database: NCT00063063.

Indexed as

Hispanic or LatinoInfant, Extremely PrematureInfant MortalityInfant, Premature, DiseasesBlack or African AmericanFemaleGestational AgeHumansInfantInfant, NewbornMaleProspective StudiesUnited StatesWhitedischargefollow-upmorbiditymortalityneurodevelopmentprematuresocial determinants of healthsocial drivers of health

Identifiers

PMID39855622
PMCPMC11903158

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Registered trials

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