Evidence map›Paper›PMID 39855620›Full record

ArticleComparative biochemistry and physiology. Part A, Molecular & integrative physiology2025

Gut microbiomes are largely unchanged when exposed to their amphibian host's latitudinally variable upper thermal limit.

Grace J Vaziri, Bryanna Caicedo, Nicole Dahrouge, William G Ryerson, Jon M Davenport, Maria Stager, Korin R Jones, Carlin Frost, Chad L Seewagen, Tracy A G Rittenhouse and 1 more

Abstract read
In one paragraph

Article in Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Grace J VaziriUniversity of Connecticut, Department of Ecology and Evolutionary Biology, 75 North Eagleville Road, Storrs, CT 06269, United States of America. Electronic address: gracevaziri@gmail.com.
Bryanna CaicedoUniversity of Connecticut, Department of Ecology and Evolutionary Biology, 75 North Eagleville Road, Storrs, CT 06269, United States of America.
Nicole DahrougeUniversity of Connecticut, Department of Natural Resources and the Environment, 1376 Storrs Road, Storrs, CT 06269, United States of America.
William G RyersonCornell University, College of Veterinary Medicine, 602 Tower Rd, Ithaca, NY 14853, United States of America.
Jon M DavenportAppalachian State University, Department of Biology, 572 Rivers Street, Boone, NC 28608, United States of America.
Maria StagerUniversity of Massachusetts Amherst, Department of Biology, Amherst, MA 01003, United States of America.
Korin R JonesUniversity of Texas at Austin, Department of Integrative Biology, 2415 Speedway #C0930, Austin, TX 78712, United States of America.
Carlin FrostUniversity of Tennessee Institute of Agriculture, School of Natural Resources, 427 Plant Biotechnology Building 2505 E.J. Chapman Drive, Knoxville, TN 37996, United States of America.
Chad L SeewagenUniversity of Connecticut, Department of Natural Resources and the Environment, 1376 Storrs Road, Storrs, CT 06269, United States of America; Great Hollow Nature Preserve & Ecological Research Center, 225 State Route 37, New Fairfield, CT 06812, United States of America.
Tracy A G RittenhouseUniversity of Connecticut, Department of Natural Resources and the Environment, 1376 Storrs Road, Storrs, CT 06269, United States of America.
Daniel I BolnickUniversity of Connecticut, Department of Ecology and Evolutionary Biology, 75 North Eagleville Road, Storrs, CT 06269, United States of America.

Funding

Reciprocal genetics of recently-evolved vertebrate immunity and peritoneal helminth counter-adaptationR01AI123659 · NIAID · UNIVERSITY OF TEXAS AT AUSTIN · PI Daniel Imara Bolnick · 2017 to 2026
$3.8M
NIAID NIH HHS R01 AI123659
6 · The paper itself

Abstract

Climate change will increase the frequency and severity of temperature extremes. Links between host thermal physiology and their gut microbiota suggest that organisms' responses to future climates may be mediated by their microbiomes, raising the question of how the thermal environment influences the microbiome itself. Vertebrate gut microbiomes influence the physiological plasticity of their hosts via effects on immunity, metabolism, and nutrient uptake. The gut microbiota of ectothermic vertebrates in particular are responsive to long-term, sub-lethal gradual increases in environmental temperature. Whether and how the gut microbiota respond to brief exposure to temperatures at the upper limit of host physiological tolerance (CT

Indexed as

AnuraGastrointestinal MicrobiomeRanidaeAnimalsClimate ChangeTemperatureAmphibianCTmaxEctothermGut microbiomeGut microbiotaThermal ecologyUpper thermal maxima

Identifiers

PMID39855620
PMCPMC12699364

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.