Evidence map›Paper›PMID 39855252›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2025

Influence of work intensity on acute kidney injury risk during simulated occupational heat stress.

Hayden W Hess, Molly E Heikkinen, Erica Tourula, M Jo Hite, Kelli Rivers, Roger S Zoh, Blair D Johnson, David Hostler, Zachary J Schlader

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Hydrating with a higher-fructose sport drink does not worsen acute kidney injury risk during simulated work-related heat stress.American journal of physiology. Regulatory, integrative and comparative physiology · 2026
    Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hayden W HessDepartment of Kinesiology, Indiana University School of Public Health-Bloomington, Bloomington, Indiana, United States.ORCID 0000-0002-8432-7208
Molly E HeikkinenDepartment of Kinesiology, Indiana University School of Public Health-Bloomington, Bloomington, Indiana, United States.
Erica TourulaDepartment of Kinesiology, Indiana University School of Public Health-Bloomington, Bloomington, Indiana, United States.ORCID 0000-0003-2937-7912
M Jo HiteDepartment of Kinesiology, Indiana University School of Public Health-Bloomington, Bloomington, Indiana, United States.
Kelli RiversDepartment of Kinesiology, Indiana University School of Public Health-Bloomington, Bloomington, Indiana, United States.
Roger S ZohDepartment of Epidemiology and Biostatistics, Indiana University School of Public Health-Bloomington, Bloomington, Indiana, United States.ORCID 0000-0002-8066-1153
Blair D JohnsonDepartment of Kinesiology, Indiana University School of Public Health-Bloomington, Bloomington, Indiana, United States.ORCID 0000-0002-1731-4415
David HostlerDepartment of Exercise and Nutrition Sciences, Center for Research and Education in Special Environments, University at Buffalo, Buffalo, New York, United States.
Zachary J SchladerDepartment of Kinesiology, Indiana University School of Public Health-Bloomington, Bloomington, Indiana, United States.ORCID 0000-0003-3590-3958

Funding

HHS | CDC | National Institute for Occupational Safety and Health (NIOSH) R01OH011528NIOSH CDC HHS R01 OH011528
6 · The paper itself

Abstract

Violation of the National Institute of Occupational Safety and Health (NIOSH) heat stress recommendations by exceeding the allowable wet bulb globe temperature (WBGT) for a given work intensity and work-rest ratio augments acute kidney injury (AKI) risk. Here, we tested the hypothesis that exceeding the allowable work intensity at a given WBGT and work-rest ratio would also worsen AKI risk. Twelve healthy adults completed two NIOSH recommendation compliant trials and one noncompliant trial consisting of a 4 h (half workday) exposure. Work-rest ratio was fixed at 30 min of walking and 30 min of rest each hour. Work intensity (metabolic heat production) was prescribed as a function of WBGT-412 ± 51 W [27.3 ± 0.3°C; high-intensity compliant (C

Indexed as

Acute Kidney InjuryHeat-Shock ResponseHeat Stress DisordersOccupational DiseasesOccupational ExposurePhysical ExertionAdultBody TemperatureFemaleHot TemperatureHumansInsulin-Like Growth Factor Binding ProteinsMaleRisk FactorsTissue Inhibitor of Metalloproteinase-2Young Adultinsulin-like growth factor binding protein-related protein 1Insulin-Like Growth Factor Binding ProteinsTIMP2 protein, humanTissue Inhibitor of Metalloproteinase-2acute kidney injuryheat stresshydrationkidney function

Identifiers

PMID39855252
PMCPMC12199259

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.