Evidence map›Paper›PMID 39854765›Full record

ReviewMedicine2025

Aggressive angiomyxoma of the vagina: A case report and literature review.

Bo Ram Yu, Won Ku Choi, Dong Hyu Cho, Na-Ri Lee

Abstract readCase ReportsReview
In one paragraph

Review in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Bo Ram YuDepartment of Obstetrics and Gynecology, Jeonbuk National University Hospital, Jeonbuk National University Medical School, Jeonju, Republic of Korea.ORCID 0000-0001-7558-5363
Won Ku ChoiDepartment of Obstetrics and Gynecology, Jeonbuk National University Hospital, Jeonbuk National University Medical School, Jeonju, Republic of Korea.ORCID 0000-0003-4891-0241
Dong Hyu ChoDepartment of Obstetrics and Gynecology, Jeonbuk National University Hospital, Jeonbuk National University Medical School, Jeonju, Republic of Korea.ORCID 0000-0002-1557-9575
Na-Ri LeeDepartment of Internal Medicine, Division of Hematology and Oncology, Jeonbuk National University Hospital, Jeonbuk National University Medical School, Jeonju, Republic of Korea.ORCID 0000-0002-6236-9319

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

rationaleAggressive angiomyxoma (AAM) is an exceptionally rare mesenchymal tumor that predominantly manifests in the female genital organs during the reproductive age. Its rarity alone makes it a fascinating subject for study. The diagnosis of AAM necessitates differentiation from other benign or mesenchymal tumors and can be confirmed through immunohistochemistry (IHC) staining. Surgical resection is the primary treatment, and adjuvant treatment can be used as hormonal therapy with gonadotropin-releasing hormone agonists, selective estrogen receptor modulators, and aromatase inhibitors. PATIENT CONCERNS: A 44-year-old premenopausal Korean woman presented with a growing perineal mass and frequent urination. DIAGNOSES: Histopathological findings confirmed AAM, with IHC staining showing estrogen receptor, progesterone receptor, actin and desmin positivity, and CD34 and S100 negativity.

interventionsThe mass was excised transvaginally under general anesthesia. OUTCOMES: The patient showed no signs of recurrence 6 months postoperatively. LESSONS: AAM in the vagina is a rare tumor that requires differential diagnosis using IHC staining. Previously, we reviewed reported cases and confirmed the feasibility and effectiveness of surgery as the main treatment. This might reassure us about the potential successful treatment of AAM. Adjuvant hormonal therapy with gonadotropin-releasing hormone agonists, selective estrogen receptor modulators, and aromatase inhibitors can further reduce the risk of recurrence.

Indexed as

MyxomaVaginal NeoplasmsAdultDiagnosis, DifferentialFemaleHumansVagina

Identifiers

PMID39854765
PMCPMC11771726

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.