Evidence map›Paper›PMID 39854621›Full record

ArticleeLife2024

Flamingo participates in multiple models of cell competition.

Pablo Sanchez Bosch, Bomsoo Cho, Jeffrey D Axelrod

Abstract read
In one paragraph

Article in eLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Imaging Cell Competition in Ex-VivoMethods and protocols · 2025
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Pablo Sanchez Bosch *Department of Pathology, Stanford University School of Medicine, Stanford, United States.ORCID https://orcid.org/0000-0002-0574-4530
Bomsoo Cho *Department of Pathology, Stanford University School of Medicine, Stanford, United States.ORCID https://orcid.org/0000-0001-8970-9160
Jeffrey D AxelrodDepartment of Pathology, Stanford University School of Medicine, Stanford, United States.ORCID https://orcid.org/0000-0001-6094-7392

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
Planar cell polarity mechanisms and systems architectureR35GM131914 · NIGMS · STANFORD UNIVERSITY · PI Jeffrey D. Axelrod · 2019 to 2026
$7.4M
NIGMS NIH HHS R35 GM131914NIH HHS P40 OD018537NIH HHS R35GM131914Swiss National Science Foundation P400PB_199258
6 · The paper itself

Abstract

The growth and survival of cells with different fitness, such as those with a proliferative advantage or a deleterious mutation, is controlled through cell competition. During development, cell competition enables healthy cells to eliminate less fit cells that could jeopardize tissue integrity, and facilitates the elimination of pre-malignant cells by healthy cells as a surveillance mechanism to prevent oncogenesis. Malignant cells also benefit from cell competition to promote their expansion. Despite its ubiquitous presence, the mechanisms governing cell competition, particularly those common to developmental competition and tumorigenesis, are poorly understood. Here, we show that in

Indexed as

Cell CompetitionDrosophila melanogasterDrosophila ProteinsAnimalsCell PolarityCell ProliferationDrosophila Proteinscell competitiondevelopmentdevelopmental biologyD. melanogasterFlamingo

Identifiers

PMID39854621
PMCPMC11684786

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.