ReviewBrain : a journal of neurology2025
The impact of resective epilepsy surgery on the brain network: evidence from post-surgical imaging.
Review in Brain : a journal of neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Application of machine learning approaches to predict seizure-onset zones in patients with drug-resistant epilepsy: a systematic review.Frontiers in neurology · 2025Pooled it
- Autonomic Network Signatures of Interictal Cardiorespiratory Dysfunction in Patients With Temporal Lobe Epilepsy.Neurology · 2026Article
- Nucleus basalis functional connectivity aberrations in temporal lobe epilepsy and improvements after successful epilepsy surgery.Epilepsia · 2026Article
- Structural Eigenmodes of the Brain to Improve the Source Localization of EEG: Application to Epileptiform Activity.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Thalamic organization differentially contributes to clinical conditions in epilepsy.Communications medicine · 2026Article
- [Adeno-associated virus-mediated gene therapy for genetic epilepsy: prospects and challenges].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2026Review
- Deciphering epileptogenic and activity-dependent gene programs in the human brain.bioRxiv : the preprint server for biology · 2026Article
- Modulation of EEG Background Rhythms in Sturge-Weber Syndrome: Impact of Surgical Timing on the Unaffected Hemisphere.Journal of central nervous system disease · 2026Article
- White matter resection and verbal memory deficits after temporal lobe epilepsy surgery.Brain communications · 2026Article
- Examining the Effectiveness of Neuropsychological Interventions on Cognition in Patients with Epilepsy: A Systematic Review and Meta-Analysis.Neuropsychology review · 2025Review
- Morphometrics of the preserved post-surgical hemisphere in pediatric drug-resistant epilepsy and implications for post-operative cognition.bioRxiv : the preprint server for biology · 2025Article
- The intraoperative SEEG andActa neurochirurgica · 2025Article
- Neighbourhood topology unveils pathological hubs in the brain networks of epilepsy-surgery patients.Brain communications · 2025Article
- Morphometrics of the preserved post-surgical hemisphere in pediatric drug-resistant epilepsy and implications for post-operative cognition.Imaging neuroscience (Cambridge, Mass.)Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Resective epilepsy surgery can be an effective treatment for patients with medication-resistant focal epilepsy. Epilepsy resection consists of the surgical removal of an epileptic focus to stop seizure generation and disrupt the epileptic network. However, even focal surgical resections for epilepsy lead to widespread brain network changes. Understanding the impact of epilepsy surgery on the brain is crucial to improve surgical outcomes for patients. Here we provide a summary of studies imaging the postsurgical effects of epilepsy resection on the brain. We focus on MRI and PET studies of temporal lobe and paediatric epilepsy, reflecting the current literature. We discuss three potential mechanisms for surgery-induced brain changes: damage and degeneration, recovery, and reorganization. We additionally review the postsurgical brain correlates of surgical outcomes as well as the potential to predict the impact of surgery on an individual patient's brain. A comprehensive characterization of the impact of surgery on the brain and precise methods to predict these brain network changes could lead to more personalized surgeries that improve seizure outcomes and reduce neuropsychological deficits after surgery.
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