ReviewJournal of magnetic resonance imaging : JMRI2025
Breast MRI to Screen Women With Extremely Dense Breasts.
Review in Journal of magnetic resonance imaging : JMRI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Rethinking Preoperative MRI in Early Breast Cancer: Who Truly Benefits?European journal of breast health · 2026Article
- Missed and true interval cancers on digital breast tomosynthesis screening mammograms: radiologists' assessment and artificial intelligence markings.Acta radiologica open · 2026Article
- Evaluation of the effect of peritumoral surrounding parenchymal features on radiological size measurement in breast cancer patients: a multicenter retrospective study (TR-BRC 2023-01).Japanese journal of radiology · 2026Article
- Article
- The Application of Nanomaterials in Breast Cancer.Pharmaceutics · 2025Review
- National policies for screening and early detection of breast cancer around the globe: Practices, barriers, and solutions.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025Review
- Monitoring Pharmacological Treatment of Breast Cancer with MRI.Current issues in molecular biology · 2025Review
- Early thelarche, reproductive hormones, and MRI-based breast density: a prospective study in China.Breast cancer research : BCR · 2025Article
- Molecular Breast Imaging with Digital Breast Tomosynthesis for Dense Breast Supplemental Screening.Radiology · 2025Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Women with extremely dense breasts are at a higher risk of breast cancer, and the sensitivity of mammography in this group is reduced due to the masking effect of overlapping tissue. This review examines supplemental screening methods to improve detection in this population, with a focus on MRI. Morphologic techniques offer limited benefits, digital breast tomosynthesis (DBT) shows inconsistent results, and ultrasound (US), while improving cancer detection rates (CDR), results in a higher rate of false positives. Functional imaging techniques show better performance, molecular breast imaging increases CDR but is limited in availability, and contrast-enhanced mammography is promising, with good results and as an accessible technique, but requires further validation. MRI, with sensitivity ranging from 81% to 100%, is the most supported modality. Despite strong evidence for MRI in this population, high costs, use of contrast, and longer scan times hinder widespread use. Abbreviated MRI protocols aim to overcome these barriers by reducing costs and scan duration. As personalized screening becomes a future focus, MRI remains the most effective option for women with extremely dense breasts. LEVEL OF EVIDENCE: 1 TECHNICAL EFFICACY: Stage 5.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.