ArticleClinical oral investigations2025
Prevalence of molar incisor hypomineralization and demands for treatment according to the severity of its clinical manifestation.
Article in Clinical oral investigations, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prevalence of developmental defects of enamel in Brazil: a systematic review and meta-analysis.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Pooled it
- Association between molar-incisor hypomineralisation and occlusal alterations in children.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Article
- Prevalence, Severity and Treatment Needs of Molar Incisor Hypomineralization Among a Cohort of Lebanese Children: A Cross-Sectional Study.Children (Basel, Switzerland) · 2026Article
- Prevalence, clinical characteristics, and treatment needs of Molar Incisor Hypomineralization (MIH) in Turkish children: a cross-sectional study.BMC public health · 2026Article
- Molar incisor hypomineralisation (MIH) and hypomineralised second primary molars (HSPM): do we need to alter terminology and definition? A scoping review.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Review
- Clinical significance of residual yellow-brown enamel opacities in severe molar incisor hypomineralisation: a cross-sectional study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Article
- Key concepts for clinical management of Molar Incisor Hypomineralization.Brazilian oral research · 2026Review
- Etch-Bleach-Seal Technique in Managing Enamel Hypomineralization: A Case Report With Narrative Literature Review.Case reports in dentistry · 2026Article
- Dentists' Knowledge, Attitudes, and Practices Regarding Molar Incisor Hypomineralization (MIH): A French Survey.Cureus · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
aimAssess the prevalence and severity of molar incisor hypomineralization (MIH) in children 6- to 12-year-old and correlate MIH severity with the complexity of treatment demands. MATERIALS AND
methodsBetween March and October 2023, 2,136 children were screened for MIH by two calibrated examiners. MIH severity was categorized in mild, moderate, severe, and very severe. Treatment requirements were categorized in basic, intermediate, and complex.
resultsThe prevalence of MIH was 15.5% (n = 331), 158 (47.7%) mild/moderate and 173 (52.3%) severe/very severe. Among the 126 children with atypical caries/restoration, cusp involvement was observed in 60.3%, endodontic treatment was necessary in 24.6%, only 15% needed restorations limited to two tooth surfaces with no cusp involvement. Extraction due to MIH was observed in 2.7%.
conclusionThe prevalence of MIH was in accordance with previous literature. Whenever a restorative treatment was necessary, it often involved multiple tooth surfaces and cusps. The complexity of treatment demands increased with age. It is necessary that oral health policymakers pay special attention to children with MIH to ensure appropriate treatment. CLINICAL RELEVANCE: MIH represents a challenge, especially severe cases with enamel post-eruptive breakdown and caries, requiring extensive restorations. MIH prevalence was assessed in a considerable large sample and the correlation between MIH severity and the complexity of treatment demands was analyzed. More than half of children exhibiting atypical caries/restorations required complex restorative treatment, involving multiple tooth surfaces and cusps. The manuscript prompts a reflection on the importance of evaluating whether the restoration will extend to cusp areas before determining the appropriate technique and material for treatment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.