SynthesisActa parasitologica2025
Toxoplasma gondii Infection in the Male Reproductive System: A Systematic Review.
Synthesis in Acta parasitologica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Beyond Latency: ChronicBiomedicines · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeToxoplasmosis is a worldwide widespread parasitic infection; it affects about 30% of the global population, either through acute toxoplasmosis or its sequels. Even though the male reproductive system is not the primary target for Toxoplasma gondii (T. gondii), studies have inquired into the possibility of presenting repercussions in this system directly or indirectly due to toxoplasmosis. Therefore, this systematic literature review aims to summarize the available evidence on the effects of infection caused by T. gondii on the male reproductive tract.
methodsWe searched PubMed, Scopus, LILACS and Google Scholar until June 2024 to identify studies of T. gondii and the human male reproductive system. Finally, we analyzed 24 papers published between 1986 and 2024. The Joanna Briggs Institute (JBI) Critical Appraisal Checklist was used to assess the potential risk of bias and the quality of the results.
resultsInfertility is a multicausal issue, including various stages in which the infection caused by T. gondii could interfere, but the mechanisms are not fully understood yet. Studies in animals, particularly rats, have shown the harmful effects of the parasite on sperm performance and endocrine function. In the same way, sexual transmission of T. gondii has been extensively studied in animals, with the parasite detected in the semen of various species. In humans, this transmission route remains theoretical due to study limitations. However, discrepancies in findings call for further research to understand the mechanisms and make the T. gondii's infection impact on the male reproductive system a topic of growing interest.
conclusionAcute and chronic infection by T. gondii in the male reproductive system is a topic of growing interest due to its possible implications for reproductive health.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.