Evidence map›Paper›PMID 39853121›Full record

ArticleAntimicrobial agents and chemotherapy2025

Lu Gao, Hao Wu, Jia Feng, Yu Liu, Ruina Wang, Lan Yan, Quanzhen Lv, Yuanying Jiang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lu Gao *Department of Pharmacology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Hao Wu *Department of Pharmacology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Jia FengDepartment of Pharmacology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Yu LiuSchool of Pharmacy, Naval Medical University, Shanghai, China.
Ruina WangSchool of Pharmacy, Naval Medical University, Shanghai, China.
Lan YanSchool of Pharmacy, Naval Medical University, Shanghai, China.ORCID 0000-0002-2617-4418
Quanzhen LvSchool of Pharmacy, Naval Medical University, Shanghai, China.ORCID 0000-0003-2045-6091
Yuanying JiangDepartment of Pharmacology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Invasive fungal infections have become an increasingly serious threat to global human health, underscoring the urgent need for the development of new antifungal drugs. In this study, we found a natural polyphenolic compound 1,2,3,4,6-O-pentagalloyl-glucose (PGG), which is present in various plants and herbs. PGG showed broad-spectrum antifungal activities, enhancing the efficacy of fluconazole. Furthermore, PGG could protect mice against gastrointestinal and systemic infection with

Indexed as

Antifungal AgentsCandida albicansCandidiasisHydrolyzable TanninsAnimalsDNA-Binding ProteinsFemaleFluconazoleHumansMiceMice, Inbred BALB CMicrobial Sensitivity TestsAntifungal AgentsDNA-Binding ProteinsFluconazoleHydrolyzable Tanninspentagalloylglucose1,2,3,4,6-O-pentagalloyl-glucoseCandida albicansEno1invasive fungal infection

Identifiers

PMID39853121
PMCPMC11881577

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.