Evidence map›Paper›PMID 39853120›Full record

ArticleAntimicrobial agents and chemotherapy2025

The stress-protectant molecule trehalose mediates fluconazole tolerance in

Qingjuan Zhu, Stefanie Wijnants, Regina Feil, Wouter Van Genechten, Rudy Vergauwen, Odessa Van Goethem, John E Lunn, Mieke Van Ende, Patrick Van Dijck

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Qingjuan ZhuDepartment of Biology, Laboratory of Molecular Cell Biology, Institute of Botany and Microbiology, KU Leuven, Leuven, Belgium.ORCID 0000-0003-4242-1623
Stefanie WijnantsDepartment of Biology, Laboratory of Molecular Cell Biology, Institute of Botany and Microbiology, KU Leuven, Leuven, Belgium.ORCID 0000-0003-2402-8860
Regina FeilMax Planck Institute of Molecular Plant Physiology, Potsdam-Golm, Germany.
Wouter Van GenechtenDepartment of Biology, Laboratory of Molecular Cell Biology, Institute of Botany and Microbiology, KU Leuven, Leuven, Belgium.ORCID 0000-0002-8562-8029
Rudy VergauwenDepartment of Biology, Laboratory of Molecular Cell Biology, Institute of Botany and Microbiology, KU Leuven, Leuven, Belgium.
Odessa Van GoethemDepartment of Biology, Laboratory of Molecular Cell Biology, Institute of Botany and Microbiology, KU Leuven, Leuven, Belgium.
John E LunnMax Planck Institute of Molecular Plant Physiology, Potsdam-Golm, Germany.
Mieke Van EndeDepartment of Biology, Laboratory of Molecular Cell Biology, Institute of Botany and Microbiology, KU Leuven, Leuven, Belgium.
Patrick Van DijckDepartment of Biology, Laboratory of Molecular Cell Biology, Institute of Botany and Microbiology, KU Leuven, Leuven, Belgium.ORCID 0000-0002-1542-897X

Funding

Fonds Wetenschappelijk Onderzoek (FWO) G0C0622NMax Planck SocietyOverseas study program of Guangzhou Elite Project S.J. [2020] No.2
6 · The paper itself

Abstract

The incidence of non-

Indexed as

Antifungal AgentsCandida glabrataFluconazoleTrehaloseDrug Resistance, FungalFungal ProteinsGlucosyltransferasesMicrobial Sensitivity TestsPhosphoric Monoester HydrolasesStress, PhysiologicalSugar PhosphatesTrehalaseAntifungal AgentsFluconazoleFungal ProteinsGlucosyltransferasesPhosphoric Monoester HydrolasesSugar PhosphatesTrehalaseTrehalosetrehalose-6-phosphatetrehalose-6-phosphate synthasetrehalose-phosphataseantifungal susceptibilityCandida glabrataergosterolfluconazoleNTH1toleranceTPS1TPS2trehalosetrehalose 6-phosphate

Identifiers

PMID39853120
PMCPMC11881567

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.