Evidence map›Paper›PMID 39853045›Full record

ReviewToxics2025

Toxicity of Per- and Polyfluoroalkyl Substances and Their Substitutes to Terrestrial and Aquatic Invertebrates-A Review.

Jiaxin Zhang, Hassan Naveed, Keping Chen, Liang Chen

Abstract readReview
In one paragraph

Review in Toxics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jiaxin ZhangSchool of Life Sciences, Jiangsu University, Zhenjiang 212013, China.
Hassan NaveedSchool of Life Sciences, Jiangsu University, Zhenjiang 212013, China.ORCID 0000-0002-9232-6299
Keping ChenSchool of Life Sciences, Jiangsu University, Zhenjiang 212013, China.ORCID 0000-0001-5254-2299
Liang ChenSchool of Life Sciences, Jiangsu University, Zhenjiang 212013, China.ORCID 0000-0003-4760-5165

Funding

National Natural Science Foundation of China Nos. 31802140Scientific Research Promotion Fund for the Talents of Jiangsu University Nos. 14JDG157
6 · The paper itself

Abstract

Per- and polyfluoroalkyl substances (PFASs) have been widely used in daily life but they cause certain impacts on the environment due to their unique carbon-fluorine chemical bonds that are difficult to degrade in the environment. Toxicological studies on PFASs and their alternatives have mainly focused on vertebrates, while terrestrial and aquatic invertebrates have been studied to a lesser extent. As invertebrates at the bottom of the food chain play a crucial role in the whole ecological chain, it is necessary to investigate the toxicity of PFASs to invertebrates. In this paper, the progress of toxicological studies on PFASs and their alternatives in terrestrial and aquatic invertebrates is reviewed, and the accumulation of PFASs, their toxicity in invertebrates, as well as the neurotoxicity and toxicity to reproduction and development are summarized. This provides a reference to in-depth studies on the comprehensive assessment of the toxicity of PFASs and their alternatives, promotes further research on PFASs in invertebrates, and provides valuable recommendations for the use and regulation of alternatives to PFASs.

Indexed as

developmental toxicityinvertebratesneurobehavioral toxicityoxidative stressperfluoroalkyl substancespolyfluoroalkyl substancesreproductive toxicitytoxicity

Identifiers

PMID39853045
PMCPMC11769487

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.