ArticleToxics2025
Exposure to Volatile Organic Compounds in Relation to Visceral Adiposity Index and Lipid Accumulation Product Among U.S. Adults: NHANES 2011-2018.
Article in Toxics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- The associations between volatile organic compounds and bone loss around teeth among US adults.BMC public health · 2026Article
- Associations of volatile organic compounds with cancer: A cross-sectional analysis of single and mixture exposures.The Journal of international medical research · 2026Article
- Association between volatile organic compounds in urine and dyslipidemia: findings based on analysis of NHANES data.Lipids in health and disease · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Volatile organic compounds (VOCs) are associated with obesity health risks, while the association of mixed VOCs with visceral adiposity indicators remains unclear. In this study, a total of 2015 adults from the National Health and Nutrition Examination Survey (NHANES) were included. Weighted generalized linear models, restricted cubic spline (RCS), weighted quantile sum (WQS), and Bayesian kernel machine regression (BKMR) were adopted to assess the association of VOC metabolites (mVOCs) with the visceral adiposity index (VAI) and lipid accumulation product (LAP). Multiple mVOCs were positively associated with the VAI and LAP in the single-exposure model, especially N-acetyl-S-(2-carboxyethyl)-L-cysteine (CEMA) and N-acetyl-S-(N-methylcarbamoyl)-L-cysteine (AMCC). The associations of mVOCs with VAI and LAP were more significant in <60-year-old and non-obese individuals, with interactions of CEMA with age and AMCC with obesity status. Nonlinear relationships between certain mVOCs and the VAI or the LAP were also observed. In the WQS model, co-exposure to mVOCs was positively correlated with the VAI [β (95%CI): 0.084 (0.022, 0.147)]; CEMA (25.24%) was the major contributor. The result of the BKMR revealed a positive trend of the association between mixed mVOCs and the VAI. Our findings suggest that VOC exposure is strongly associated with visceral obesity indicators. Further large prospective investigations are necessary to support our findings.
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