Evidence map›Paper›PMID 39852985›Full record

ArticleToxins2025

Encapsulated LyeTx III Peptide: Cytotoxic Agent Isolated from

Daniel Moreira Dos Santos, Livia Ramos Santiago, Nayara Araújo Dos Santos, Wanderson Romão, Jarbas Magalhães Resende, Maria Elena de Lima, Márcia Helena Borges, Rosy Iara Maciel de Azambuja Ribeiro

Abstract read
In one paragraph

Article in Toxins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Daniel Moreira Dos SantosDepartment of Experimental Pathology, Federal University of São João del-Rei, Divinópolis 36301-158, Brazil.ORCID 0000-0002-2599-035X
Livia Ramos SantiagoDepartment of Experimental Pathology, Federal University of São João del-Rei, Divinópolis 36301-158, Brazil.ORCID 0000-0002-9288-2519
Nayara Araújo Dos SantosPetroleomics and Forensics Laboratory, Federal University of Espírito Santo, Vitória 29075-910, Brazil.
Wanderson RomãoPetroleomics and Forensics Laboratory, Federal University of Espírito Santo, Vitória 29075-910, Brazil.
Jarbas Magalhães ResendeDepartment of Chemistry, Federal University of Minas Gerais (UFMG), Belo Horizonte 30110-005, Brazil.ORCID 0000-0001-9827-7312
Maria Elena de LimaPrograma de Pós-Graduação em Medicina-Biomedicina, Faculdade Santa Casa de Belo Horizonte, Belo Horizonte 30110-005, Brazil.ORCID 0000-0001-6185-4032
Márcia Helena BorgesProteomics and Arachnid Laboratory, Ezequiel Dias Foundation, Belo Horizonte 30110-005, Brazil.
Rosy Iara Maciel de Azambuja RibeiroDepartment of Experimental Pathology, Federal University of São João del-Rei, Divinópolis 36301-158, Brazil.ORCID 0000-0002-7374-4743

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior code 001Fundação de Amparo à pesquisa do Estado de Minas Gerais FAPEMIG-PPM-00229-16 and APQ-00068-18
6 · The paper itself

Abstract

The discovery of novel cytotoxic drugs is of paramount importance in contemporary medical research, particularly in the search for treatments with fewer side effects and higher specificity. Antimicrobial peptides are an interesting class of molecules for this endeavor. In this context, the LyeTx III, a new peptide extracted from the venom of the

Indexed as

Antineoplastic AgentsSpider VenomsAmino Acid SequenceAnimalsCell Line, TumorCell SurvivalHumansLiposomesSpidersAntineoplastic AgentsLiposomesSpider Venomsantimicrobial peptidesantitumor activityencapsulated peptidespider venom

Identifiers

PMID39852985
PMCPMC11768708

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.