Evidence map›Paper›PMID 39852969›Full record

ArticleToxins2025

Exposure to Subclinical Doses of Fumonisins, Deoxynivalenol, and Zearalenone Affects Immune Response, Amino Acid Digestibility, and Intestinal Morphology in Broiler Chickens.

Revathi Shanmugasundaram, Laharika Kappari, Mohammad Pilewar, Matthew K Jones, Oluyinka A Olukosi, Anthony Pokoo-Aikins, Todd J Applegate, Anthony E Glenn

Abstract read
In one paragraph

Article in Toxins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Efficacy of Toxfin in Mitigating Mycotoxin Effects in Laying Hens.Animals : an open access journal from MDPI · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Revathi ShanmugasundaramU. S. National Poultry Research Center, Agriculture Research Service, U.S. Department of Agriculture, Athens, GA 30605, USA.ORCID 0000-0003-0546-6902
Laharika KappariDepartment of Poultry Science, University of Georgia, Athens, GA 30602, USA.ORCID 0009-0003-8277-157X
Mohammad PilewarDepartment of Poultry Science, University of Georgia, Athens, GA 30602, USA.
Matthew K JonesSouthern Poultry Research Group, Inc., Watkinsville, GA 30677, USA.
Oluyinka A OlukosiDepartment of Poultry Science, University of Georgia, Athens, GA 30602, USA.ORCID 0000-0002-9137-6745
Anthony Pokoo-AikinsU. S. National Poultry Research Center, Agriculture Research Service, U.S. Department of Agriculture, Athens, GA 30605, USA.ORCID 0000-0001-9778-3053
Todd J ApplegateDepartment of Poultry Science, University of Georgia, Athens, GA 30602, USA.
Anthony E GlennU. S. National Poultry Research Center, Agriculture Research Service, U.S. Department of Agriculture, Athens, GA 30605, USA.ORCID 0000-0001-8329-1306

Funding

USDA- ARS 6040-42000-046-000D.
6 · The paper itself

Abstract

Fusarium mycotoxins often co-occur in broiler feed, and their presence negatively impacts health even at subclinical concentrations, so there is a need to identify the concentrations of these toxins that do not adversely affect chickens health and performance. The study was conducted to evaluate the least toxic effects of combined mycotoxins fumonisins (FUM), deoxynivalenol (DON), and zearalenone (ZEA) on the production performance, immune response, intestinal morphology, and nutrient digestibility of broiler chickens. A total of 960 one-day-old broilers were distributed into eight dietary treatments: T1 (Control); T2: 33.0 FUM + 3.0 DON + 0.8 ZEA; T3: 14.0 FUM + 3.5 DON + 0.7 ZEA; T4: 26.0 FUM + 1.0 DON + 0.2 ZEA; T5: 7.7 FUM + 0.4 DON + 0.1 ZEA; T6: 3.6 FUM + 2.5 DON + 0.9 ZEA; T7: 0.8 FUM + 1.0 DON + 0.3 ZEA; T8: 1.0 FUM + 0.5 DON + 0.1 ZEA, all in mg/kg diet. The results showed that exposure to higher mycotoxin concentrations, T2 and T3, had significantly reduced body weight gain (BWG) by 17% on d35 (

Indexed as

ChickensFumonisinsIntestinesTrichothecenesZearalenoneAmino AcidsAnimal FeedAnimalsDigestionAmino AcidsdeoxynivalenolFumonisinsTrichothecenesZearalenoneamino acid digestibilitybroilersimmune responseintestinal healthmycotoxins

Identifiers

PMID39852969
PMCPMC11769399

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.