Evidence map›Paper›PMID 39852918›Full record

ArticleVeterinary sciences2025

Control of Neonatal Diarrhea in Piglets with Reduced Antibiotic Use by Application of a Complementary Feed-A Randomized Controlled Farm Trial.

Klaus K Sall, Leslie Foldager, Charlotte Delf, Sigurd J Christensen, Michael N Agerley, Kristian T Havn, Carsten Pedersen

Abstract read
In one paragraph

Article in Veterinary sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Klaus K SallSall&Sall Advisors, DK-8220 Brabrand, Denmark.ORCID 0009-0004-4396-1087
Leslie FoldagerDepartment of Animal and Veterinary Sciences, Aarhus University, DK-8830 Tjele, Denmark.ORCID 0000-0002-2639-826X
Charlotte Delf6360 Tinglev, Denmark.
Sigurd J ChristensenNewtrifeed ApS, DK-6372 Bylderup-Bov, Denmark.
Michael N AgerleyNewtrifeed ApS, DK-6372 Bylderup-Bov, Denmark.
Kristian T HavnNewtrifeed ApS, DK-6372 Bylderup-Bov, Denmark.
Carsten PedersenPedersen Nutrition, Ltd., Shaftesbury GB-SP7 9QG, UK.

Funding

Newtrifeed ApS No grant number
6 · The paper itself

Abstract

The objective of this farm trial was to investigate if the consumption of antibiotics could be reduced when piglets showing early signs of neonatal diarrhea were treated with an oral dose of tannin extract derived from sweet chestnut wood. The farm had a very high incidence of neonatal diarrhea among gilt litters. Gilts were randomized into test or control groups in a 1:1 ratio to compare the consumption of antibiotics used for piglets and piglet mortality during the four-week trial period. Control litters were treated with the oral antibiotic paromomycin, while test litters were treated with the complementary feed O-Nella-Protect. The farm trial included 18 gilt litters comprising 254 piglets. In the control group, 100% of the piglets received antibiotic treatment. In the test group, consumption of antibiotics used against diarrhea was reduced by 84% (

Indexed as

Castanea sativaClostridium perfringensneonatal diarrheaO-Nella-Protectpigletpolyphenolerandomized controlled trialRCTRotavirusRWAtannin extract

Identifiers

PMID39852918
PMCPMC11769454

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.