Evidence map›Paper›PMID 39852899›Full record

ArticleVeterinary sciences2025

Glycerol Monolaurate Complex Improved Antioxidant, Anti-Inflammation, and Gut Microbiota Composition of Offspring in a Sow-Piglet Model.

Dan Li, Min Yang, Zhao Ma, Lianqiang Che, Bin Feng, Zhengfeng Fang, Shengyu Xu, Yong Zhuo, Jian Li, JiHhua Wang and 5 more

Abstract read
In one paragraph

Article in Veterinary sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Dan LiKey Laboratory of Animal Disease-Resistance Nutrition and Feed Science, Institute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China.
Min YangPet Nutrition and Health Research Center, Chengdu Agricultural College, Chengdu 611130, China.
Zhao MaKey Laboratory of Animal Disease-Resistance Nutrition and Feed Science, Institute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China.
Lianqiang CheKey Laboratory of Animal Disease-Resistance Nutrition and Feed Science, Institute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China.
Bin FengKey Laboratory of Animal Disease-Resistance Nutrition and Feed Science, Institute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China.ORCID 0000-0001-6258-2729
Zhengfeng FangKey Laboratory of Animal Disease-Resistance Nutrition and Feed Science, Institute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China.
Shengyu XuKey Laboratory of Animal Disease-Resistance Nutrition and Feed Science, Institute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China.ORCID 0000-0002-4415-8542
Yong ZhuoKey Laboratory of Animal Disease-Resistance Nutrition and Feed Science, Institute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China.ORCID 0000-0002-8348-4199
Jian LiKey Laboratory of Animal Disease-Resistance Nutrition and Feed Science, Institute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China.
JiHhua WangCalid Biotech (Wuhan) Co., Ltd., Wuhan 430073, China.
Zhengfan ZhangHubei Key Laboratory of Animal Nutrition and Feed Science, Wuhan Polytechnic University, Wuhan 430023, China.
Zehui WuSichuan Qiaozhu'er Breeding Co., Ltd., Neijiang 641100, China.
Tao LinKey Laboratory of Animal Disease-Resistance Nutrition and Feed Science, Institute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China.
De WuKey Laboratory of Animal Disease-Resistance Nutrition and Feed Science, Institute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China.
Yan LinKey Laboratory of Animal Disease-Resistance Nutrition and Feed Science, Institute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China.

Funding

Sichuan Swine Innovation Team of National Modern Agricultural Industry Technology System sccxtd-2024the Natural Science Foundation of Sichuan Province 2022NSFSC0058the Sichuan Major Science and Technology Projects 2021ZDZX0009
6 · The paper itself

Abstract

This study aimed to investigate the effects of maternal glycerol monolaurate complex (GML) and antibiotic (acetylisovaleryltylosin tartrate, ATLL) supplementation during late gestation and lactation on the reproductive performance of sows and the growth performance of piglets. In total, 64 pregnant sows were randomly divided into control, antibiotic, 0.1% GML, and 0.2% GML groups. The GML shortened their delivery interval and farrowing duration. The ATLL increased the level of malondialdehyde (MDA) in sows and piglets and enhanced glutathione peroxidase (GSH-Px) in piglets, while reducing the tumor necrosis factor-α (TNF-α) level in sows. The GML tended to increase milk protein in the colostrum and decreased the TNF-α of sows at lactation. Meanwhile, 0.2% GML increased the serum total superoxide dismutase (T-SOD) activity and interleukin-6 level in weaned piglets and decreased the TNF-α level in sows and weaned piglets. Furthermore, ATLL decreased the microbial diversity of sows, and GML tended to increase the microbial diversity of sows and piglets. The ATLL group had an increased relative abundance of Bacteroidota in weaned piglets. The GML decreased the relative abundance of Peptostreptococcales-Tissierellales, Proteobacteria, and the harmful bacteria

Indexed as

fecal microbialglycerol monolaurate complexpigletsreproductivesows

Identifiers

PMID39852899
PMCPMC11769162

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.