Evidence map›Paper›PMID 39852884›Full record

ArticleVeterinary sciences2024

Genome-Wide Genomic Analysis and Evolutionary Insights into Bovine Coronavirus Strains in Southwest China.

Qingqing Li, Huili Bai, Yan Pan, Yuying Liao, Zhe Pei, Cuilan Wu, Chunxia Ma, Zhongwei Chen, Changting Li, Yu Gong and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Veterinary sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Qingqing LiCollege of Animal Science and Technology, Guangxi University, Nanning 530004, China.
Huili BaiCollege of Animal Science and Technology, Guangxi University, Nanning 530004, China.
Yan PanCollege of Animal Science and Technology, Guangxi Agricultural Vocational and Technical University, Nanning 530007, China.
Yuying LiaoGuangxi Key Laboratory of Veterinary Biotechnology, Guangxi Veterinary Research Institute, Nanning 530001, China.
Zhe PeiSchool of Neuroscience, The City College of New York, New York, NY 10031, USA.
Cuilan WuCollege of Animal Science and Technology, Guangxi University, Nanning 530004, China.
Chunxia MaCollege of Animal Science and Technology, Guangxi University, Nanning 530004, China.
Zhongwei ChenGuangxi Key Laboratory of Veterinary Biotechnology, Guangxi Veterinary Research Institute, Nanning 530001, China.
Changting LiGuangxi Key Laboratory of Veterinary Biotechnology, Guangxi Veterinary Research Institute, Nanning 530001, China.
Yu GongGuizhou Animal Husbandry and Veterinary Research Institute, Guiyang 550005, China.
Jing LiuGuizhou Animal Husbandry and Veterinary Research Institute, Guiyang 550005, China.
Yangyan YinGuangxi Key Laboratory of Veterinary Biotechnology, Guangxi Veterinary Research Institute, Nanning 530001, China.
Ling TengGuangxi Key Laboratory of Veterinary Biotechnology, Guangxi Veterinary Research Institute, Nanning 530001, China.
Leping WangGuangxi Key Laboratory of Veterinary Biotechnology, Guangxi Veterinary Research Institute, Nanning 530001, China.ORCID 0000-0002-0986-4476
Ezhen ZhangInstitute of Agricultural Products Processing, Guangxi Academy of Agricultural Sciences, Nanning 530007, China.
Tianchao WeiCollege of Animal Science and Technology, Guangxi University, Nanning 530004, China.ORCID 0009-0000-8633-2353
Hao PengGuangxi Key Laboratory of Veterinary Biotechnology, Guangxi Veterinary Research Institute, Nanning 530001, China.ORCID 0000-0002-9619-5628

Funding

Hao Peng Guangxi Agriculture Technology Program,z202228Hao Peng Guangxi Basic Scientific Research Project,22-6, 24-2Hao Peng Guangxi Innovation Team Construction Project of National Modern Agricultural Industry Technology System,nycytxgxcxtd20210905Hao Peng Guangxi Key Research and Development Program,AB21238003Hao Peng Laibin Key Research and Development Programme,220819, 240113Hao Peng Liangqing Key Research and Development Program,202118Yu Gong Guizhou agricultural animal and plant breeding project,NY [2018]016Yu Gong Guizhou Beef Cattle Industry Technology System Construction Project,GZCYTX-03Yu Gong Guizhou Science and Technology Program,20201Y075, 20203009-3
6 · The paper itself

Abstract

The global epidemic of bovine coronavirus (BCoV) has caused enormous economic losses. The characterisation and genetic composition of endemic strains in Southwest China remain elusive. This study aimed to fill this gap by isolating three BCoV strains from this region and sequencing their whole genomes. To elucidate the genetic evolution and characterisation of the prevalent strains, the results of BCoV sequences were compared in GenBank, with a focus on genetic evolution, mutation, and recombination patterns. The results showed close homology between strains NN190313 and NN230328, while strain NN221214 showed less similarity to these two strains but clustered with the French strain of the European branch. Intriguingly, NN190313 and NN230328 were grouped with goat-derived BCoV strains from Jiangsu Province in Eastern China in the Asian-American branch. In addition, recombination analyses revealed significant signals between NN230328 and either a Chinese goat-derived strain (XJCJ2301G) or a Shandong strain (ShX310). This study highlights the importance of monitoring cross-species transmission between cattle and goats, especially in the mountainous areas of Southwest China where mixed farming occurs, and thus, the monitoring of cross-species transmission between cattle and goats is important for preventing new public health challenges, providing important insights for research on cross-species transmission, early prevention, and control measures, with potential applications in vaccine development.

Indexed as

bovine coronaviruscross-species transmissiongenetic evolution analysiswhole-genome sequencing

Identifiers

PMID39852884
PMCPMC11769207

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.