Evidence map›Paper›PMID 39852842›Full record

ArticleVaccines2025

Determinants of Rotavirus Vaccine Acceptance in an Area of Southern Italy with Low Vaccination Coverage: A Case-Control Study by the Health Belief Model Questionnaire.

Davide Anzà, Massimiliano Esposito, Giorgio Bertolazzi, Alessandra Fallucca, Carlo Genovese, Gabriele Maniscalco, Andrea D Praticò, Tiziana Scarpaci, Ermanno Vitale, Vincenzo Restivo

Abstract read
In one paragraph

Article in Vaccines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Davide AnzàDepartment of Medicine and Surgery, University of Enna Kore, 94100 Enna, Italy.
Massimiliano EspositoDepartment of Medicine and Surgery, University of Enna Kore, 94100 Enna, Italy.ORCID 0000-0001-7880-3450
Giorgio BertolazziDepartment of Medicine and Surgery, University of Enna Kore, 94100 Enna, Italy.ORCID 0000-0001-7328-9675
Alessandra FalluccaDepartment of Health Promotion, Maternal and Infant Care, Internal Medicine and Medical Specialties (PROMISE) "G. D'Alessandro", University of Palermo, 90127 Palermo, Italy.ORCID 0000-0002-5303-9609
Carlo GenoveseDepartment of Medicine and Surgery, University of Enna Kore, 94100 Enna, Italy.ORCID 0000-0003-2463-9047
Gabriele ManiscalcoDepartment of Health Promotion, Maternal and Infant Care, Internal Medicine and Medical Specialties (PROMISE) "G. D'Alessandro", University of Palermo, 90127 Palermo, Italy.
Andrea D PraticòDepartment of Medicine and Surgery, University of Enna Kore, 94100 Enna, Italy.
Tiziana ScarpaciDepartment of Health Promotion, Maternal and Infant Care, Internal Medicine and Medical Specialties (PROMISE) "G. D'Alessandro", University of Palermo, 90127 Palermo, Italy.
Ermanno VitaleDepartment of Medicine and Surgery, University of Enna Kore, 94100 Enna, Italy.ORCID 0000-0002-0152-0214
Vincenzo RestivoDepartment of Medicine and Surgery, University of Enna Kore, 94100 Enna, Italy.ORCID 0000-0002-5406-884X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesRotavirus (RV) is the primary cause of gastroenteritis in children worldwide, contributing significantly to morbidity and mortality, particularly among children under five years of age. The introduction of Rotavirus vaccines (RVV) has markedly reduced RV-related childhood deaths, especially in Europe, where substantial reductions in hospitalizations and disease prevalence have been observed. Despite these advances, RVV uptake in Italy remains below the desired targets, with notable regional disparities. In Sicily, vaccination rates have fluctuated, with current coverage failing to meet national goals. Safety concerns and insufficient parental awareness are major barriers to RVV acceptance.

methodsThis case-control study was conducted in Southern Italy to identify factors influencing parental acceptance of RVV. Data were collected from parents using a structured questionnaire that assessed socio-demographic factors, vaccine knowledge, and attitudes based on the Health Belief Model (HBM).

resultsOverall, 226 parents were enrolled. Higher perceived benefit of RVV was significantly associated with increased vaccine adherence (Odds Ratio = 13.65; 95% Confidence Interval = 6.88-27.09;

conclusionsThese results highlight the need for targeted interventions to improve vaccine coverage and address regional and socio-economic barriers to RVV acceptance. Furthermore, tailored educational campaigns and univocal information from healthcare providers could play pivotal roles in achieving higher vaccine uptake.

Indexed as

acute gastroenteritishealth belief modelhospital admissionparents acceptancerotavirusvaccination coveragevaccine refusal

Identifiers

PMID39852842
PMCPMC11769460

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.