ArticleVaccines2024
The Epidemiology and Health Burdens of Influenza Infections Amongst Hospitalized Children Under 5 Years of Age in Jordan: A National Multi-Center Cross-Sectional Study.
Article in Vaccines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The trial behind it
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Who cites it
4 citing papers in PubMed.
- Article
- National Cross-Sectional Study Assessing the Positivity Rate and Clinical Manifestations of Human Bocavirus Respiratory Infections Among Hospitalized Children Under 5 Years of Age in Jordan.Pathogens (Basel, Switzerland) · 2026Article
- Knowledge, attitudes, barriers and uptake rate of influenza virus vaccine among children from 6 months to 5 years of age in Jordan: a multicentric cross-sectional study.Italian journal of pediatrics · 2025Article
- Patterns of the Circulation of Influenza in a Targeted Jordanian Subpopulation from November 2021 to April 2023.Pathogens (Basel, Switzerland) · 2025Article
Corrections and comments
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Authors and funding
17 authors.
Funding
Abstract
BACKGROUND/
objectivesSeasonal influenza is a significant global health concern, causing substantial morbidity and mortality, particularly among high-risk groups such as children under five years old. There is scarce local evidence from developing countries such as Jordan on the burden of influenza, which has limited preventive measures. This multi-center national cross-sectional study aimed to assess the epidemiological and clinical burden of influenza among hospitalized children under five years old in Jordan.
methodsData were collected from 1000 participants across four hospitals between November 2022 and April 2023. Nasopharyngeal specimens were analyzed using multiplex RT-PCR to determine positivity for influenza A and B.
resultsWe found a 9.9% positivity rate, predominantly influenza A (8.4%), while influenza B was positive among 1.5% of the participants. Positivity rates were higher in older age groups, particularly children older than 2 years. Influenza-positive cases exhibited longer fever durations and higher rates of sore throat. There were no positive influenza cases among participants if they or any of their family members received the influenza vaccine, highlighting the vaccine's protective role. Logistic regression analysis identified maternal smoking during pregnancy as a significant predictor of influenza positivity.
conclusionsThe findings of this study underscore the need for enhanced vaccination efforts and public health policies targeting young children and pregnant women in Jordan. Expanding vaccination uptake could significantly mitigate the burden of influenza and its complications in this vulnerable population.
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