Evidence map›Paper›PMID 39852673›Full record

ArticleTropical medicine and infectious disease2025

Description of the Serological Response After Treatment of Chronic Imported Schistosomiasis.

Marta González-Sanz, Irene Martín-Rubio, Oihane Martín, Alfonso Muriel, Sagrario de la Fuente-Hernanz, Clara Crespillo-Andújar, Sandra Chamorro-Tojeiro, Begoña Monge-Maíllo, Francesca F Norman, José A Pérez-Molina

Abstract read
In one paragraph

Article in Tropical medicine and infectious disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Observational
  4. Case Report: Uncommon presentation ofFrontiers in medicine · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Marta González-SanzNational Reference Centre for Imported Tropical Diseases, Infectious Diseases Department, Hospital Universitario Ramón y Cajal, IRYCIS, 28034 Madrid, Spain.ORCID 0000-0002-3252-9748
Irene Martín-RubioNational Reference Centre for Imported Tropical Diseases, Infectious Diseases Department, Hospital Universitario Ramón y Cajal, IRYCIS, 28034 Madrid, Spain.ORCID 0000-0001-5471-5843
Oihane MartínCIBERINFEC, Instituto de Salud Carlos III, 28029 Madrid, Spain.
Alfonso MurielDepartamento de Medicina y Especialidades Médicas, Programa de Ciencias de la Salud, Universidad de Alcalá, 28801 Alcalá de Henares, Spain.
Sagrario de la Fuente-HernanzNational Reference Centre for Imported Tropical Diseases, Microbiology Department, Hospital Universitario Ramón y Cajal, IRYCIS, 28034 Madrid, Spain.
Clara Crespillo-AndújarNational Reference Centre for Imported Tropical Diseases, Infectious Diseases Department, Hospital Universitario Ramón y Cajal, IRYCIS, 28034 Madrid, Spain.
Sandra Chamorro-TojeiroNational Reference Centre for Imported Tropical Diseases, Infectious Diseases Department, Hospital Universitario Ramón y Cajal, IRYCIS, 28034 Madrid, Spain.ORCID 0000-0003-0960-1630
Begoña Monge-MaílloNational Reference Centre for Imported Tropical Diseases, Infectious Diseases Department, Hospital Universitario Ramón y Cajal, IRYCIS, 28034 Madrid, Spain.
Francesca F NormanNational Reference Centre for Imported Tropical Diseases, Infectious Diseases Department, Hospital Universitario Ramón y Cajal, IRYCIS, 28034 Madrid, Spain.
José A Pérez-MolinaNational Reference Centre for Imported Tropical Diseases, Infectious Diseases Department, Hospital Universitario Ramón y Cajal, IRYCIS, 28034 Madrid, Spain.ORCID 0000-0001-8735-4124

Funding

Center for Biomedical Research in Infectious Diseases Network (CIBERINFEC) and Epidemiology and Public Health Networking Biomedical Research Center (CIBERESP), Instituto de Salud Carlos III N/A
6 · The paper itself

Abstract

backgroundChronic schistosomiasis can lead to significant morbidity. Serology is highly sensitive; however, its role in assessing treatment response is controversial. This study aimed to analyze serological values following treatment of chronic imported schistosomiasis.

methodsA retrospective observational study was performed including patients treated for chronic imported schistosomiasis from 2018 to 2022 who had at least one serological result at baseline and during follow-up. Demographic, clinical, and laboratory data were evaluated. Generalized estimating equation (GEE) models and Kaplan-Meier curves were used to analyze the evolution of serological values.

resultsOf the 83 patients included, 72 (86.7%) were male, and the median age was 26 years (IQR 22-83). Most patients, 76 (91.6%), were migrants from sub-Saharan Africa. While 24 cases (28.9%) presented with urinary symptoms, the majority (59; 71.1%) were asymptomatic.

conclusionsSerial serological determinations could be helpful for monitoring chronic schistosomiasis in non-endemic regions. The ideal timing for these follow-up tests is yet to be determined. Further research is needed to determine the factors that influence a negative result during follow-up.

Indexed as

diagnosismigrant healthneglected tropical diseasesschistosomiasisserologytravelers

Identifiers

PMID39852673
PMCPMC11768958

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.