Evidence map›Paper›PMID 39852658›Full record

ReviewTropical medicine and infectious disease2024

The Impact of Onchocerciasis Elimination Measures in Africa: A Systematic Review.

Policarpo Ncogo, Christine Giesen, María Jesús Perteguer, Maria P Rebollo, Rufino Nguema, Agustín Benito, Zaida Herrador

Abstract readReview
In one paragraph

Review in Tropical medicine and infectious disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Policarpo NcogoFundación Estatal, Salud, Infancia y Bienestar Social (FCSAI), 28029 Madrid, Spain.
Christine GiesenCentro de Salud Internacional Madrid Salud, Ayuntamiento de Madrid, 28006 Madrid, Spain.ORCID 0000-0002-5026-9724
María Jesús PerteguerCentro Nacional de Microbiología, Instituto de Salud Carlos III, 28220 Madrid, Spain.
Maria P RebolloExpanded Special Project for Elimination of Neglected Tropical Disease (ESPEN), WHO World Health Organization-African Region, P.O.Box 06 Brazzaville, Congo.
Rufino NguemaMinisterio de Sanidad y Bienestar Social, Balboa Calle Mayor, Malabo QQ2H+8WC, Equatorial Guinea.
Agustín BenitoConsorcio de Investigación Biomédica en Red Enfermedades Infecciosas (CIBERINFEC), 28029 Madrid, Spain.ORCID 0000-0001-8229-5540
Zaida HerradorCentro Nacional de Epidemiología, Instituto de Salud Carlos III, 28029 Madrid, Spain.ORCID 0000-0002-6508-3818

Funding

World Health Organization 001
6 · The paper itself

Abstract

backgroundOnchocerciasis, or river blindness, is one of the neglected tropical diseases (NTDs) that the WHO has set out to eliminate. To reach this elimination target, a number of challenges must be met, and the essential measures set out in the road map for NTDs 2021-2030 must be implemented. More than 99% of infected people live in 31 countries in sub-Saharan Africa. Our objective was to assess the impact of onchocerciasis interventions in Africa. METHODOLOGY: A systematic peer review of the existing literature following the PRISMA guidelines was performed between November 2021 and April 2022. We selected studies on onchocerciasis control measures in Africa since the implementation of the first Onchocerciasis Control Programme (OCP) measures in 1974. All scientific articles indexed in the PubMed, Scopus, Embase, and CENTRAL databases written in Spanish, English, French, German, and Portuguese were considered. The study protocol was registered in the PROSPERO database.

resultsA total of 63 articles met the inclusion criteria and were finally selected. Publications were found from 19 out of 31 African endemic countries. The main intervention retained in the different published studies was mass distribution of ivermectin (

conclusionsControl interventions showed a positive impact on the fight against onchocerciasis, demonstrating that these activities are effective. Nevertheless, they were not sufficient to achieve the proposed goals for a variety of reasons. Therefore, different aspects should be considered in order to fulfil the targets proposed by the WHO to be reached in 2030.

Indexed as

Africacommunity directed treatmentcontrol measuresonchocerciasis

Identifiers

PMID39852658
PMCPMC11768683

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.