Evidence map›Paper›PMID 39852568›Full record

ArticleJournal of functional biomaterials2025

Next-Generation Dental Materials: Exploring Bacterial Biofilm Formation on 3D-Printable Resin-Based Composites.

Emerson Koji Uehara, Gustavo Castro de Lima, Janaina de Cassia Orlandi Sardi, Luciene Cristina de Figueiredo, Jamil Awad Shibli, Thabet Asbi, Doron Haim, José Augusto Rodrigues

Abstract read
In one paragraph

Article in Journal of functional biomaterials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Emerson Koji UeharaDental Research Division, Guarulhos University, Guarulhos 07023-070, SP, Brazil.
Gustavo Castro de LimaDental Research Division, Guarulhos University, Guarulhos 07023-070, SP, Brazil.
Janaina de Cassia Orlandi SardiDental Research Division, Guarulhos University, Guarulhos 07023-070, SP, Brazil.ORCID 0000-0002-8500-2691
Luciene Cristina de FigueiredoDental Research Division, Guarulhos University, Guarulhos 07023-070, SP, Brazil.
Jamil Awad ShibliDental Research Division, Guarulhos University, Guarulhos 07023-070, SP, Brazil.ORCID 0000-0003-1971-0195
Thabet AsbiDental Research Division, Guarulhos University, Guarulhos 07023-070, SP, Brazil.ORCID 0000-0002-1875-7402
Doron HaimMaccabi-Dent Research Department, Tel-Aviv 6801298, Israel.
José Augusto RodriguesDental Research Division, Guarulhos University, Guarulhos 07023-070, SP, Brazil.ORCID 0000-0003-4172-1499

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study evaluated the microbial growth profile of subgingival multispecies biofilm on 3D-printable resin-based composites (PRBCs). A 96-well cell plate cultivated a 39-species biofilm associated with periodontitis over 7 days. Cylindrical specimens with 12 mm high and 3 mm diameters were prepared by the PRBC group (Cosmos Temp-Yller; Prizma 3D Bio Crown; Prizma 3D Bio Prov) and an acrylic resin as control. Further, these specimens were immersed in the well plate to allow biofilm formation. After growing for 7 days, the metabolic biofilm activity was evaluated by colorimetric assay and the microbial profile by DNA-DNA hybridization. Kruskal-Wallis and Mann-Whitney tests evaluated each bacteria count and complex group. A greater biofilm formation was observed on PRBC groups than on acrylic resin. The microbiological profile of PRBC was associated with a less pathogenic biofilm, with an absence of a red complex. Acrylic resin showed low biofilm growth, but the biofilm profile was related to periodontal disease, characterized by red-complex bacteria. The selection of PRBC may contribute more effectively to maintaining periodontal health than acrylic resin.

Indexed as

3D printed resinsadditive manufacturingantimicrobial activitycomputer-aided designperiodontal diseaseperiodontal pathogens

Identifiers

PMID39852568
PMCPMC11765569

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.