Evidence map›Paper›PMID 39852011›Full record

ArticleGels (Basel, Switzerland)2025

Exploring Methacrylated Gellan Gum 3D Bioprinted Patches Loaded with Tannic Acid or L-Ascorbic Acid as Potential Platform for Wound Dressing Application.

Federica Scalia, Alessandra Maria Vitale, Domiziana Picone, Noemi De Cesare, Maria Swiontek Brzezinska, Beata Kaczmarek-Szczepanska, Alfredo Ronca, Barbara Zavan, Fabio Bucchieri, Marta Anna Szychlinska and 1 more

Abstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Federica ScaliaDepartment of Biomedicine, Neuroscience and Advanced Diagnostics (BIND), University of Palermo, 90127 Palermo, Italy.ORCID 0000-0001-9948-9712
Alessandra Maria VitaleDepartment of Biomedicine, Neuroscience and Advanced Diagnostics (BIND), University of Palermo, 90127 Palermo, Italy.ORCID 0000-0002-7566-4309
Domiziana PiconeDepartment of Biomedicine, Neuroscience and Advanced Diagnostics (BIND), University of Palermo, 90127 Palermo, Italy.
Noemi De CesareInstitute of Polymers, Composites and Biomaterials (IPCB), National Research Council (CNR), 80125 Naples, Italy.
Maria Swiontek BrzezinskaDepartment of Environmental Microbiology and Biotechnology, Faculty of Biological and Veterinary Sciences, Nicolaus Copernicus University in Torun, Lwowska 1, 87-100 Torun, Poland.
Beata Kaczmarek-SzczepanskaDepartment of Biomaterials and Cosmetics Chemistry, Faculty of Chemistry, Nicolaus Copernicus University in Torun, Gagarin 7, 87-100 Torun, Poland.ORCID 0000-0002-2563-2376
Alfredo RoncaInstitute of Polymers, Composites and Biomaterials (IPCB), National Research Council (CNR), 80125 Naples, Italy.ORCID 0000-0002-6658-004X
Barbara ZavanDepartment of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0002-4779-4456
Fabio BucchieriDepartment of Biomedicine, Neuroscience and Advanced Diagnostics (BIND), University of Palermo, 90127 Palermo, Italy.
Marta Anna SzychlinskaDepartment of Precision Medicine in Medical, Surgical and Critical Care (MEPRECC), University of Palermo, 90127 Palermo, Italy.
Ugo D'AmoraInstitute of Polymers, Composites and Biomaterials (IPCB), National Research Council (CNR), 80125 Naples, Italy.ORCID 0000-0002-6142-059X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To improve wound healing, advanced biofabrication techniques are proposed here to develop customized wound patches to release bioactive agents targeting cell function in a controlled manner. Three-dimensional (3D) bioprinted "smart" patches, based on methacrylated gellan gum (GGMA), loaded with tannic acid (TA) or L-ascorbic acid (AA) have been manufactured. To improve stability and degradation time, gellan gum (GG) was chemically modified by grafting methacrylic moieties on the polysaccharide backbone. GGMA patches were characterized through physicochemical, morphological and mechanical evaluation. Kinetics release and antioxidant potential of TA and AA as well as antimicrobial activity against common pathogens

Indexed as

3D bioprintingL-ascorbic acidmethacrylated gellan gum patchestannic acidwound healing

Identifiers

PMID39852011
PMCPMC11765158

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.