ReviewGels (Basel, Switzerland)2025
Fundamentals and Advances in Stimuli-Responsive Hydrogels and Their Applications: A Review.
Review in Gels (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
74 citing papers in PubMed.
- The expanding role of biocompatible hydrogels in plant-derived exosome-like nanovesicles for skin diseases: prospects and challenges.Annals of medicine · 2026Review
- Next-generation smart polymeric hydrogels for chronic wound management: integrating antimicrobial, immunomodulatory and regenerative strategies.RSC advances · 2026Review
- Hydrogel-Based Depot Systems in Psychiatric Pharmacotherapy: A Narrative Review Rethinking Long-Acting Drug Delivery.Gels (Basel, Switzerland) · 2026Review
- Engineering Hydrogels for Intrauterine Adhesion Therapy and Endometrial Regeneration.Gels (Basel, Switzerland) · 2026Review
- Data-Driven Development of Biomedical Hydrogels for Controlled Drug Delivery: Clinical Applications and Emerging Machine-Learning Approaches.Journal of functional biomaterials · 2026Review
- Rapid Photogelation of Low-Concentration Polymer Solutions via Photodimerization of o-Ethylnitrobenzene.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Hydrogels for Local Drug Delivery in Biofilm-Associated Periprosthetic Joint Infection: Current Progress and Future Directions.Microorganisms · 2026Review
- Efficient Preparation of pH-Sensitive Core-Shell Drug-Loaded Hydrogel Microcapsules and Their Application in Ulcerative Colitis Treatment.Gels (Basel, Switzerland) · 2026Article
- Clinical translation and engineering challenges of soft robotic cardiac sleeves for heart failure.Nature communications · 2026Review
- Effects of Different Lignin Contents and Water Contents on the Performance of DES-Based Hydrogels.Gels (Basel, Switzerland) · 2026Article
- Programmable Hydrogels for Surgical Interface Control: Function-Based Design, DNA-Based Molecular Modules, and Translational Evaluation.Gels (Basel, Switzerland) · 2026Review
- Biopolymer-Based Hydrogels for Wound Healing: Advances in Cellulose, Chitosan, Alginate, and Hyaluronic Acid from Design to Clinical Translation.Pharmaceuticals (Basel, Switzerland) · 2026Review
- Emerging Nanobiochar -Hydrogel Therapeutic Systems: Redox Modulation, Biointerface Interactions, and Critical Gaps in In Vitro Evaluation.Gels (Basel, Switzerland) · 2026Review
- Redefining Stability in Cultural Heritage Through Polymer Design: From Conservation Strategies to Plastic Degradation.Polymers · 2026Review
- Sustainable Cellulose-Based Gels: Synthesis, Chemical Modification, and Biomedical Application.Gels (Basel, Switzerland) · 2026Review
- Multifunctional Hydrogels for Diabetic Wound Healing: Design Strategies and Microenvironmental Remodeling Mechanisms.Gels (Basel, Switzerland) · 2026Review
- Intelligent Hydrocolloid-Based Delivery Systems: Innovations in Pharmacy and Cosmetics.Molecules (Basel, Switzerland) · 2026Review
- Editorial for the Special Issue "Gel Formation Processes and Materials for Functional Thin Films (1st Edition)".Gels (Basel, Switzerland) · 2026Article
- Hydrogel-Based Sensors: Compositions, Fabrication, Sensing Mechanism, and Applications.Polymers · 2026Review
- Recapitulating Endochondral Ossification for Bone Repair: From Development to Engineering Strategy.Advanced healthcare materials · 2026Review
14 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
This review summarizes the fundamental concepts, recent advancements, and emerging trends in the field of stimuli-responsive hydrogels. While numerous reviews exist on this topic, the field continues to evolve dynamically, and certain research directions are often overlooked. To address this, we classify stimuli-responsive hydrogels based on their response mechanisms and provide an in-depth discussion of key properties and mechanisms, including swelling kinetics, mechanical properties, and biocompatibility/biodegradability. We then explore hydrogel design, synthesis, and structural engineering, followed by an overview of applications that are relatively well established from a scientific perspective, including biomedical uses (biosensing, drug delivery, wound healing, and tissue engineering), environmental applications (heavy metal and phosphate removal from the environment and polluted water), and soft robotics and actuation. Additionally, we highlight emerging and unconventional applications such as local micro-thermometers and cell mechanotransduction. This review concludes with a discussion of current challenges and future prospects in the field, aiming to inspire further innovations and advancements in stimuli-responsive hydrogel research and applications to bring them closer to the societal needs.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.