Evidence map›Paper›PMID 39851936›Full record

ArticleCurrent oncology (Toronto, Ont.)2024

Implementation of a Hepatitis B Screening Program in Patients Receiving Systemic Anti-Cancer Therapy.

Jennifer Leigh, Ranjeeta Mallick, Stephanie Brule, Lisa Rambout, Jennifer Newton, Dominick Bossé, Curtis Cooper, Joanna Gotfrit

Abstract read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jennifer LeighDivision of Medical Oncology, Department of Medicine, The Ottawa Hospital, Ottawa, ON K1H 8L6, Canada.ORCID 0000-0002-7431-3574
Ranjeeta MallickOttawa Hospital Research Institute, Ottawa, ON K1H 8L6, Canada.
Stephanie BruleDivision of Medical Oncology, Department of Medicine, The Ottawa Hospital, Ottawa, ON K1H 8L6, Canada.
Lisa RamboutThe Ottawa Hospital Pharmacy Department, Ottawa, ON K1H 8L6, Canada.
Jennifer NewtonThe Ottawa Hospital, Ottawa, ON K1H 8L6, Canada.
Dominick BosséDivision of Medical Oncology, Department of Medicine, The Ottawa Hospital, Ottawa, ON K1H 8L6, Canada.ORCID 0000-0003-2992-5632
Curtis CooperDivision of Infectious Diseases, Department of Medicine, The Ottawa Hospital, Ottawa, ON K1Y 4E9, Canada.ORCID 0000-0002-3368-3499
Joanna GotfritDivision of Medical Oncology, Department of Medicine, The Ottawa Hospital, Ottawa, ON K1H 8L6, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer patients receiving non-endocrine therapies are at risk of hepatitis B virus (HBV) reactivation (HBVr). Guidelines recommend HBV screening prior to treatment. The Ottawa Hospital Cancer Center implemented a screening pilot for all patients receiving FOLFOX-based regimens between January and April 2023. We assessed the pilot from a quality improvement perspective. Charts were retrospectively reviewed, and patient and disease characteristics were collected. The primary endpoint was to identify the proportion of patients who underwent HBV screening prior to treatment start. Univariate analyses assessed the association between baseline characteristics and failure to screen. Quality metrics were also reviewed. There were 32/42 patients (76.2%) who completed screening, and 5 (11.9%) had a positive screen. The majority of eligible patients (59.5%) completed screening prior to the first treatment as intended. Four of five patients who tested positive were referred to Infectious Diseases. Of those, one received antivirals for chronic HBV. There were no treatment delays due to pending screening and no HBV reactivation. Receipt of prior systemic therapy was significantly associated with failure to screen (55 vs. 95%, OR 17.1 (95% CI 1.92-153),

Indexed as

Hepatitis BMass ScreeningNeoplasmsAgedFemaleHepatitis B virusHumansMaleMiddle AgedRetrospective Studiescolorectal cancergastrointestinal cancerhepatitis B viral reactivationhepatitis B virusscreening

Identifiers

PMID39851936
PMCPMC11764458

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.