Evidence map›Paper›PMID 39851931›Full record

ReviewCurrent oncology (Toronto, Ont.)2024

Focal Therapy for Prostate Cancer: Recent Advances and Insights.

Francesco Lasorsa, Arianna Biasatti, Angelo Orsini, Gabriele Bignante, Gabriana M Farah, Savio Domenico Pandolfo, Luca Lambertini, Deepika Reddy, Rocco Damiano, Pasquale Ditonno and 3 more

Abstract readReview
In one paragraph

Review in Current oncology (Toronto, Ont.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Francesco LasorsaDepartment of Urology, Rush University, Chicago, IL 60612, USA.ORCID 0000-0001-8884-0757
Arianna BiasattiDepartment of Urology, Rush University, Chicago, IL 60612, USA.
Angelo OrsiniDepartment of Urology, Rush University, Chicago, IL 60612, USA.ORCID 0009-0009-9372-5847
Gabriele BignanteDepartment of Urology, Rush University, Chicago, IL 60612, USA.ORCID 0009-0008-4269-6663
Gabriana M FarahDepartment of Urology, Rush University, Chicago, IL 60612, USA.
Savio Domenico PandolfoDepartment of Urology, University of L'Aquila, 67100 L'Aquila, Italy.ORCID 0000-0001-9621-3059
Luca LambertiniDepartment of Experimental and Clinical Medicine, Careggi Hospital, University of Florence, 50121 Florence, Italy.
Deepika ReddyNHS Imperial College London, London W2 1NY, UK.ORCID 0000-0001-6889-0378
Rocco DamianoDepartment of Urology, Magna Graecia University, 88100 Catanzaro, Italy.
Pasquale DitonnoDepartment of Precision and Regenerative Medicine and Ionian Area-Urology, Andrology and Kidney Transplantation Unit, University of Bari "Aldo Moro", 70121 Bari, Italy.ORCID 0000-0001-7718-7676
Giuseppe LucarelliDepartment of Precision and Regenerative Medicine and Ionian Area-Urology, Andrology and Kidney Transplantation Unit, University of Bari "Aldo Moro", 70121 Bari, Italy.ORCID 0000-0001-7807-1229
Riccardo AutorinoDepartment of Urology, Rush University, Chicago, IL 60612, USA.ORCID 0000-0001-7045-7725
Srinivas VourgantiDepartment of Urology, Rush University, Chicago, IL 60612, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Focal therapy has emerged as a balanced middle ground aiming to reduce overtreatment and the risk of progression, as well as patients' distress and anxiety. Focal therapy and partial gland ablation prioritize the precise elimination of the index lesion and a surrounding safety margin to optimize treatment outcomes and lower the risk of residual disease. The paradigm of whole-gland ablation has shifted towards more targeted approaches. Several treatment templates ranging from subtotal and hemiablation to "hockey-stick", quadrant, and even focal lesion ablation have emerged. Many types of energy may be utilized during focal treatment. First, focal therapy can be grossly classified into thermal vs. non-thermal energy. The aim of this non-systematic review is to offer a comprehensive analysis of recently available evidence on focal therapy for PCa.

Indexed as

Ablation TechniquesProstatic NeoplasmsHumansMaleablationfocal therapyprostate cancer

Identifiers

PMID39851931
PMCPMC11764426

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.