Evidence map›Paper›PMID 39851542›Full record

ArticleCells2025

Imaging Flow Cytometric Identification of Chromosomal Defects in Paediatric Acute Lymphoblastic Leukaemia.

Ana P A Simpson, Carly E George, Henry Y L Hui, Ravi Doddi, Rishi S Kotecha, Kathy A Fuller, Wendy N Erber

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ana P A SimpsonSchool of Biomedical Sciences, The University of Western Australia, Crawley, WA 6009, Australia.
Carly E GeorgeDepartment of Clinical Haematology, Oncology, Blood and Marrow Transplantation, Perth Children's Hospital, Perth, WA 6009, Australia.ORCID 0000-0003-4982-4871
Henry Y L HuiSchool of Biomedical Sciences, The University of Western Australia, Crawley, WA 6009, Australia.
Ravi DoddiSchool of Biomedical Sciences, The University of Western Australia, Crawley, WA 6009, Australia.
Rishi S KotechaDepartment of Clinical Haematology, Oncology, Blood and Marrow Transplantation, Perth Children's Hospital, Perth, WA 6009, Australia.ORCID 0000-0003-1836-4075
Kathy A FullerSchool of Biomedical Sciences, The University of Western Australia, Crawley, WA 6009, Australia.
Wendy N ErberSchool of Biomedical Sciences, The University of Western Australia, Crawley, WA 6009, Australia.ORCID 0000-0002-1028-9376

Funding

Channel 7 Telethon Trust 2019ErberNational Health and Medical Research Council APP2004957Raine Medical Research Foundation RPG027-2022
6 · The paper itself

Abstract

Acute lymphoblastic leukaemia is the most common childhood malignancy that remains a leading cause of death in childhood. It may be characterised by multiple known recurrent genetic aberrations that inform prognosis, the most common being hyperdiploidy and t(12;21)

Indexed as

Chromosome AberrationsFlow CytometryPrecursor Cell Lymphoblastic Leukemia-LymphomaAdolescentAneuploidyChildChild, PreschoolCore Binding Factor Alpha 2 SubunitETS Translocation Variant 6 ProteinFemaleHumansImmunophenotypingInfantIn Situ Hybridization, FluorescenceMaleOncogene Proteins, FusionCore Binding Factor Alpha 2 SubunitETS Translocation Variant 6 ProteinOncogene Proteins, FusionProto-Oncogene Proteins c-etsRepressor ProteinsRUNX1 protein, humanTEL-AML1 fusion proteinacute lymphoblastic leukaemiaETV6::RUNX1hyperdiploidimaging flow cytometryimmuno-flowFISH

Identifiers

PMID39851542
PMCPMC11763943

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.