Evidence map›Paper›PMID 39851494›Full record

ArticleCells2025

Comprehensive Analysis Identifies

Jianan Chen, Qiong Wu, Anders E Berglund, Robert J Macaulay, Arnold B Etame

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jianan ChenDepartment of Neuro-Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.ORCID 0000-0002-6673-6884
Qiong WuDepartment of Neuro-Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.ORCID 0000-0001-9712-0647
Anders E BerglundDepartment of Biostatistics and Bioinformatics, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, FL 33612, USA.ORCID 0000-0002-0393-3530
Robert J MacaulayDepartments of Anatomic Pathology, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, FL 33612, USA.ORCID 0000-0003-1115-3654
Arnold B EtameDepartment of Neuro-Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.ORCID 0000-0002-9656-4702

Funding

Targeting Malignant Reprogramming of Glioblastoma Stem Cells Through Dual Inhibition of S6K1 and BIRC3R01NS135220 · NINDS · H. LEE MOFFITT CANCER CTR & RES INST · PI Arnold Etame · 2024 to 2026
$1.7M
Exploiting Epigenetic Vulnerabilities In Glioblastoma Stem Cells Through ReprogrammingR21CA264635 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI ETAME, ARNOLD · 2022 to 2022
$433k
NCI NIH HHS 1R21CA264635NCI NIH HHS R21 CA264635NINDS NIH HHS 1R01NS135220NINDS NIH HHS R01 NS135220
6 · The paper itself

Abstract

Glioblastoma (GBM) is a highly aggressive brain tumor characterized by its ability to evade the immune system, hindering the efficacy of current immunotherapies. Recent research has highlighted the important role of immunosuppressive macrophages in the tumor microenvironment (TME) in driving this immune evasion. In this study, we are the first to identify

Indexed as

Biomarkers, TumorBrain NeoplasmsGlioblastomaAnimalsCell Line, TumorFemaleGene Expression Regulation, NeoplasticHumansMaleMicePhagocytosisPrognosisTumor-Associated MacrophagesTumor MicroenvironmentBiomarkers, Tumorglioblastomamacrophage-mediated immunosuppressionprognosisTHEMIS2tumor microenvironment

Identifiers

PMID39851494
PMCPMC11764009

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.