Evidence map›Paper›PMID 39851479›Full record

ArticleDiseases (Basel, Switzerland)2025

The Development and Initial Validation of the REST Questionnaire: A Multidimensional Tool for Assessing Fatigue in Individuals with and Without a History of Cancer.

Giuseppe Di Lorenzo, Carlo Buonerba, Raffaele Baio, Eleonora Monteleone, Francesco Passaro, Antonio Tufano, Vittorino Montanaro, Vittorio Riccio, Ilaria Gallo, Francesca Cappuccio and 8 more

Abstract read
In one paragraph

Article in Diseases (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

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4 · The record

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5 · Who and what money

Authors and funding

18 authors.

Giuseppe Di LorenzoOncology Unit, "Andrea Tortora" Hospital, ASL Salerno, 84016 Pagani, Italy.
Carlo BuonerbaOncology Unit, "Andrea Tortora" Hospital, ASL Salerno, 84016 Pagani, Italy.
Raffaele BaioDepartment of Urology, Umberto I, Nocera Inferiore, 84014 Salerno, Italy.ORCID 0000-0002-3157-0845
Eleonora MonteleoneDepartment of Urology, Istituito Nazionale Tumori IRCCS Fondazione G. Pascale, 80131 Napoli, Italy.ORCID 0009-0008-8328-8797
Francesco PassaroDepartment of Urology, Istituito Nazionale Tumori IRCCS Fondazione G. Pascale, 80131 Napoli, Italy.
Antonio TufanoDepartment of Urology, Istituito Nazionale Tumori IRCCS Fondazione G. Pascale, 80131 Napoli, Italy.
Vittorino MontanaroUrology Unit, San Leonardo Hospital, Castellammare Di Stabia, 80053 Naples, Italy.
Vittorio RiccioOspedale S. Maria della Pietà, 80026 Casoria, Italy.
Ilaria GalloPrimary Care Department, ASL Salerno (SA), 84016 Pagani, Italy.
Francesca CappuccioOncology Unit, "Andrea Tortora" Hospital, ASL Salerno, 84016 Pagani, Italy.
Federica FortinoOncology Unit, "Andrea Tortora" Hospital, ASL Salerno, 84016 Pagani, Italy.
Anna BuonocorePrimary Care Department, ASL Salerno (SA), 84016 Pagani, Italy.
Federica MonacoDepartment of Anesthesia, San Paolo Hospital ASL Napoli 1 Centro, 80125 Naples, Italy.ORCID 0000-0002-5986-3594
Antonio VerdeOncology Unit, "Andrea Tortora" Hospital, ASL Salerno, 84016 Pagani, Italy.
Anna Rita AmatoOncology Unit, "Andrea Tortora" Hospital, ASL Salerno, 84016 Pagani, Italy.
Oriana StrianeseOncology Unit, "Andrea Tortora" Hospital, ASL Salerno, 84016 Pagani, Italy.
Ferdinando CostabileOncology Unit, "Andrea Tortora" Hospital, ASL Salerno, 84016 Pagani, Italy.
Luca ScafuriOncology Unit, "Andrea Tortora" Hospital, ASL Salerno, 84016 Pagani, Italy.ORCID 0000-0002-7410-8300

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFatigue is a prevalent and complex condition with significant impacts on well-being. Existing fatigue assessments often lack comprehensiveness or practicality for general population studies.

methodsThis study validated the REST Questionnaire, a novel fatigue assessment tool, in a sample of 268 adults. Psychometric properties, including internal consistency and construct validity, were evaluated. REST scores were correlated with WHO-5 well-being, BMI, self-rated health, and chronic conditions. Exploratory factor analysis identified underlying dimensions of fatigue.

resultsThe REST Questionnaire demonstrated excellent internal consistency (Cronbach's alpha = 0.918) and construct validity. Higher fatigue scores were associated with lower well-being, female gender, and the presence of certain chronic conditions (cancer, kidney stones, gastric ulcers). Two distinct fatigue dimensions, "physical fatigue and functional impacts" and "emotional and social consequences", were identified.

conclusionsThe REST Questionnaire is a reliable and valid tool for assessing fatigue in the general population. Its multidimensional framework and sensitivity to comorbidities offer valuable insights for research and public health applications, with the potential to inform targeted interventions aimed at improving well-being.

Indexed as

chronic conditionsfatigue assessmentpsychometricspublic healthREST questionnairevalidation studywell-being

Identifiers

PMID39851479
PMCPMC11764002

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