Evidence map›Paper›PMID 39851447›Full record

ReviewBrain sciences2025

Digital Interventions for the Rehabilitation of First-Episode Psychosis: An Integrated Perspective.

Annarita Vignapiano, Francesco Monaco, Ernesta Panarello, Stefania Landi, Benedetta Di Gruttola, Raffaele Malvone, Vassilis Martiadis, Fabiola Raffone, Alessandra Marenna, Maria Pontillo and 4 more

Abstract readReview
In one paragraph

Review in Brain sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Annarita VignapianoDepartment of Mental Health, ASL Salerno, 84125 Salerno, Italy.ORCID 0009-0004-8301-3401
Francesco MonacoDepartment of Mental Health, ASL Salerno, 84125 Salerno, Italy.ORCID 0000-0002-1854-292X
Ernesta PanarelloDepartment of Mental Health, ASL Salerno, 84125 Salerno, Italy.
Stefania LandiDepartment of Mental Health, ASL Salerno, 84125 Salerno, Italy.
Benedetta Di GruttolaDepartment of Mental Health, ASL Salerno, 84125 Salerno, Italy.
Raffaele MalvoneDepartment of Mental Health, ASL Salerno, 84125 Salerno, Italy.ORCID 0009-0000-5924-6046
Vassilis MartiadisDepartment of Mental Health, ASL Napoli 1 Centro, 80125 Napoli, Italy.ORCID 0000-0002-3344-1000
Fabiola RaffoneDepartment of Mental Health, ASL Napoli 1 Centro, 80125 Napoli, Italy.ORCID 0000-0002-1818-4237
Alessandra MarennaEuropean Biomedical Research Institute of Salerno (EBRIS), 84125 Salerno, Italy.
Maria PontilloChild & Adolescent Neuropsychiatry Unit, Bambino Gesù Children's Hospital, IRCCS, 00146 Rome, Italy.
Valeria Di StefanoPsychiatric Unit, Department of Health Sciences, University Magna Graecia of Catanzaro, 88100 Catanzaro, Italy.ORCID 0009-0006-2333-0637
Martina D'AngeloPsychiatric Unit, Department of Health Sciences, University Magna Graecia of Catanzaro, 88100 Catanzaro, Italy.
Luca SteardoPsychiatric Unit, Department of Health Sciences, University Magna Graecia of Catanzaro, 88100 Catanzaro, Italy.ORCID 0000-0002-7077-3506
Giulio CorrivettiDepartment of Mental Health, ASL Salerno, 84125 Salerno, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe integration of digital health technologies has transformed mental healthcare, particularly for young adults with First-Episode Psychosis (FEP). Digital interventions, such as telepsychiatry and mobile applications, address barriers like social stigma, restricted access to services, and the urgency of timely care.

methodsA systematic literature review was conducted using PubMed and APA PsycINFO. Included studies focused on randomized controlled trials, cohort studies, and open studies of digital interventions for FEP rehabilitation. Exclusion criteria included meta-analyses, reviews, and irrelevant studies.

resultsSmartphone applications like Horyzons-Canada facilitated peer support and symptom management, while tools such as My Journey 3 emphasized the need for better user engagement. Digital innovations, including Cognitive Behavioral Therapy for insomnia (CBT-I) and telepsychiatry, demonstrated improvements in recovery and treatment adherence. DISCUSSION: Digital interventions significantly enhance the accessibility and quality of FEP care, supporting functional recovery and patient engagement. Future research should prioritize longitudinal studies, user engagement strategies, and advanced analytics to develop personalized, scalable solutions.

Indexed as

digital devicefirst-episode psychosismental health technologiesmobile mental health apps

Identifiers

PMID39851447
PMCPMC11763830

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.