Evidence map›Paper›PMID 39851369›Full record

ArticleBrain sciences2024

Regression-Based Classification of the Middle-Latency Auditory-Evoked Potentials in Vestibular Migraine and Concussion Patients with Dizziness.

Carolina Beppi, Daniel Agostino, Antonella Palla, Nina Feddermann-Demont, Julia Dlugaiczyk, Dominik Straumann

Abstract read
In one paragraph

Article in Brain sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Carolina BeppiNeuroscience Center Zurich, University and ETH Zurich, CH-8091 Zurich, Switzerland.
Daniel AgostinoInterdisciplinary Center for Neurological and Vestibular Disorders, Department of Neurology, University Hospital Zurich, CH-8091 Zurich, Switzerland.
Antonella PallaInterdisciplinary Center for Neurological and Vestibular Disorders, Department of Neurology, University Hospital Zurich, CH-8091 Zurich, Switzerland.
Nina Feddermann-DemontSports Neuroscience, University of Zurich, CH-8006 Zurich, Switzerland.
Julia DlugaiczykInterdisciplinary Center for Neurological and Vestibular Disorders, Department of Neurology, University Hospital Zurich, CH-8091 Zurich, Switzerland.ORCID 0000-0001-7693-9127
Dominik StraumannNeuroscience Center Zurich, University and ETH Zurich, CH-8091 Zurich, Switzerland.ORCID 0000-0002-5349-7650

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesThe auditory middle-latency responses (AMLRs) assess central sensory processing beyond the brainstem and serve as a measure of sensory gating. They have clinical relevance in the diagnosis of neurological conditions. In this study, magnitude and habituation of the AMLRs were tested for sensitivity and specificity in classifying dizzy patients with vestibular migraine (VM) and post-concussive syndrome.

methodsTwenty-three healthy individuals, 12 concussion and 26 VM patients were recruited. AMLR were recorded performing five blocks of 200 binaural click-stimulations at 60 dB sensation level with a repetition rate of 6.1 Hz. Reduction in P0, Na and Pa magnitudes between blocks was measured. Group classifications were performed through logistic and multiple regression.

resultsAmong healthy subjects, a consistent P0 and Na habituation can be observed. Concussed subjects show control-like Na habituation, despite a lower magnitude, while P0 habituation was negligible. VM patients showed poor habituation for all waves. Regression analyses suggest that P0 and Na better distinguish healthy subjects from neurological patients, whereas Pa best distinguishes concussion from VM patients.

conclusionsThe results support that AMLR habituation can contribute to unraveling different mechanisms of dizziness due to concussion compared to VM, providing insights that can complement routine diagnostic assessments.

Indexed as

auditory-evoked potentialsconcussiongroup classificationhabituationlogistic regressionmultiple regressionvestibular migraine

Identifiers

PMID39851369
PMCPMC11763820

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.