Evidence map›Paper›PMID 39851319›Full record

ReviewBioengineering (Basel, Switzerland)2025

The Application of Terahertz Technology in Corneas and Corneal Diseases: A Systematic Review.

Bing Jie Chow, Chang Liu, Mingyi Yu, Isabelle Xin Yu Lee, Jodhbir S Mehta, Qing Yang Steve Wu, Regina Wong Kay Ting, Ke Lin, Yu-Chi Liu

Abstract readReview
In one paragraph

Review in Bioengineering (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. In Vivo T-Cell Engineering: Revolution in Delivery Strategies and Clinical Translation.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2026
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Bing Jie ChowBarts and the London School of Medicine and Dentistry, Queen Mary University of London, London E1 2AD, UK.ORCID 0000-0002-5787-0563
Chang LiuTissue Engineering and Cell Therapy Group, Singapore Eye Research Institute, Singapore 169856, Singapore.
Mingyi YuTissue Engineering and Cell Therapy Group, Singapore Eye Research Institute, Singapore 169856, Singapore.
Isabelle Xin Yu LeeTissue Engineering and Cell Therapy Group, Singapore Eye Research Institute, Singapore 169856, Singapore.
Jodhbir S MehtaTissue Engineering and Cell Therapy Group, Singapore Eye Research Institute, Singapore 169856, Singapore.
Qing Yang Steve WuInstitute of Materials Research and Engineering, Agency for Science, Technology and Research, Singapore 138634, Singapore.ORCID 0000-0003-2525-8334
Regina Wong Kay TingTissue Engineering and Cell Therapy Group, Singapore Eye Research Institute, Singapore 169856, Singapore.
Ke LinInstitute of Materials Research and Engineering, Agency for Science, Technology and Research, Singapore 138634, Singapore.
Yu-Chi LiuTissue Engineering and Cell Therapy Group, Singapore Eye Research Institute, Singapore 169856, Singapore.ORCID 0000-0001-5408-0382

Funding

SingHealth Duke-NUS Academic Medical Centre R2023/66/2023
6 · The paper itself

Abstract

Terahertz (THz) waves reside in the electromagnetic spectrum between the microwave and infrared bands. In recent decades, THz technology has demonstrated its potential for biomedical applications. With the highly unique characteristics of THz waves, such as the high sensitivity to water and optimal spatial resolution coupled with the characteristics of the human cornea, such as its high water content, THz technology has been explored as a potential modality to assess corneas and corneal diseases. This systematic review provides an overview of the characteristics of THz waves, the safety profile of THz technology in the field of ophthalmology, and its clinical applications, including the objective evaluation of the corneal hydration, tear film, dry eye disease, corneal endothelium, corneal elasticity, and scarring. The paper also presents our viewpoint on the present challenges and future directions of THz technology prior to its broader integration into clinical practice.

Indexed as

corneal hydrationcorneal scarscorneasdry eyeterahertz

Identifiers

PMID39851319
PMCPMC11762122

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.