Evidence map›Paper›PMID 39851289›Full record

ArticleBioengineering (Basel, Switzerland)2024

Are Collagen Protons Visible with the Zero Echo Time (ZTE) Magnetic Resonance Imaging Sequence: A D

Tan Guo, Dina Moazamian, Arya A Suprana, Saeed Jerban, Eric Y Chang, Yajun Ma, Michael Carl, Min Chen, Jiang Du

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tan GuoDepartment of Radiology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing 100730, China.ORCID 0000-0003-1149-5849
Dina MoazamianDepartment of Radiology, University of California San Diego, San Diego, CA 92037, USA.
Arya A SupranaDepartment of Radiology, University of California San Diego, San Diego, CA 92037, USA.
Saeed JerbanDepartment of Radiology, University of California San Diego, San Diego, CA 92037, USA.ORCID 0000-0001-6450-2892
Eric Y ChangDepartment of Radiology, University of California San Diego, San Diego, CA 92037, USA.ORCID 0000-0003-3633-5630
Yajun MaDepartment of Radiology, University of California San Diego, San Diego, CA 92037, USA.
Michael CarlGE Healthcare, San Diego, CA 92123, USA.
Min ChenDepartment of Radiology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing 100730, China.
Jiang DuDepartment of Radiology, University of California San Diego, San Diego, CA 92037, USA.ORCID 0000-0002-9203-2450

Funding

Ultrashort Echo Time (UTE) Magnetic Resonance Imaging of BoneR01AR068987 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DU, JIANG · 2015 to 2024
$4.9M
Quantitative UTE MR Imaging: Sensitive Biomarkers for OsteoarthritisR01AR062581 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DU, JIANG · 2013 to 2022
$4.1M
Ultrashort Echo Time Magnetic Resonance Imaging of the Lumbar Intervertebral Disc.R01AR079484 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Yajun Ma · 2022 to 2026
$2.7M
Quantitative UTE MR Imaging of Myelin: Novel Biomarkers for Alzheimer's DiseaseRF1AG075717 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DU, JIANG · 2022 to 2022
$2.3M
Three-dimensional Ultrashort Echo Time Magnetic Resonance Imaging of EnthesesR01AR075825 · NIAMS · VETERANS MEDICAL RESEARCH FDN/SAN DIEGO · PI CHANG, ERIC Y · 2019 to 2023
$1.8M
Knee evaluation under mechanical loading by cones ultrashort echo time MR imagingK01AR080257 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI saeed jerban · 2022 to 2026
$602k
BLRD VA I01 BX005952CSRD VA I01 CX002211GE Healthcare.NIAMS NIH HHS K01 AR080257NIAMS NIH HHS R01 AR062581NIAMS NIH HHS R01 AR068987NIAMS NIH HHS R01 AR075825NIAMS NIH HHS R01 AR079484NIA NIH HHS RF1 AG075717NIH HHS 1R01 AR062581, 1R01 AR068987, R01AR075825, R01AR079484, RF1AG075717, and K01AR080257VA Clinical Science Research & Development Service I01CX002211, and I01BX005952
6 · The paper itself

Abstract

It is known that ultrashort echo time (UTE) magnetic resonance imaging (MRI) sequences can detect signals from water protons but not collagen protons in short T2 species such as cortical bone and tendons. However, whether collagen protons are visible with the zero echo time (ZTE) MRI sequence is still unclear. In this study, we investigated the potential of the ZTE MRI sequence on a clinical 3T scanner to directly image collagen protons via D

Indexed as

collagenD2O–H2O exchangemagnetic resonance imaging (MRI)ultrashort echo time (UTE)zero echo time (ZTE)

Identifiers

PMID39851289
PMCPMC11763331

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.