Evidence map›Paper›PMID 39851286›Full record

ArticleBioengineering (Basel, Switzerland)2024

Glioma Image-Level and Slide-Level Gene Predictor (GLISP) for Molecular Diagnosis and Predicting Genetic Events of Adult Diffuse Glioma.

Minh-Khang Le, Masataka Kawai, Kenta Masui, Takashi Komori, Takakazu Kawamata, Yoshihiro Muragaki, Tomohiro Inoue, Ippei Tahara, Kazunari Kasai, Tetsuo Kondo

Abstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Minh-Khang LeDepartment of Pathology, University of Yamanashi, Yamanashi 409-3898, Japan.ORCID 0000-0002-4571-0888
Masataka KawaiDepartment of Pathology, University of Yamanashi, Yamanashi 409-3898, Japan.ORCID 0000-0003-1106-239X
Kenta MasuiDepartment of Pathology, Tokyo Women's Medical University, Tokyo 162-8666, Japan.ORCID 0000-0002-5824-6690
Takashi KomoriDepartment of Laboratory Medicine and Pathology (Neuropathology), Tokyo Metropolitan Neurological Hospital, Tokyo 183-0042, Japan.ORCID 0000-0002-6812-2149
Takakazu KawamataDepartment of Neurosurgery, Tokyo Women's Medical University, Shinjuku, Tokyo 162-8666, Japan.ORCID 0000-0002-6076-7065
Yoshihiro MuragakiCenter for Advanced Medical Engineering Research and Development, Kobe University, Kobe 650-0047, Hyogo, Japan.ORCID 0000-0001-8336-5328
Tomohiro InoueDepartment of Pathology, University of Yamanashi, Yamanashi 409-3898, Japan.
Ippei TaharaDepartment of Pathology, University of Yamanashi, Yamanashi 409-3898, Japan.
Kazunari KasaiDepartment of Pathology, University of Yamanashi, Yamanashi 409-3898, Japan.
Tetsuo KondoDepartment of Pathology, University of Yamanashi, Yamanashi 409-3898, Japan.

Funding

New Energy and Industrial Technology Development Organization JPNP20006
6 · The paper itself

Abstract

The latest World Health Organization (WHO) classification of central nervous system tumors (WHO2021/5th) has incorporated molecular information into the diagnosis of each brain tumor type including diffuse glioma. Therefore, an artificial intelligence (AI) framework for learning histological patterns and predicting important genetic events would be useful for future studies and applications. Using the concept of multiple-instance learning, we developed an AI framework named GLioma Image-level and Slide-level gene Predictor (GLISP) to predict nine genetic abnormalities in hematoxylin and eosin sections:

Indexed as

artificial intelligencedeep learninggenetic abnormalitiesgliomanew WHO classification

Identifiers

PMID39851286
PMCPMC11761954

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.