ArticleCirculation. Arrhythmia and electrophysiology2025
Effect of Sequential, Colocalized Radiofrequency and Pulsed Field Ablation on Cardiac Lesion Size and Histology.
Article in Circulation. Arrhythmia and electrophysiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.
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Who cites it
33 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Ventricular pulsed field ablation from bench to bedside: preclinical and clinical evidence from a systematic review and meta-analysis.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026Pooled it
- Pulsed field ablation for the interventional treatment of atrial fibrillation: a scientific statement of the European Heart Rhythm Association of the European Society of Cardiology, the Heart Rhythm Society, the Asia Pacific Heart Rhythm Society, the Latin American Heart Rhythm Society, and the Canadian Heart Rhythm Society.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026Guideline
- Combined Endocardial Pulsed Field: Radiofrequency Ablation of a 3-Dimensional Ventricular Tachycardia With MidMyocardial Isthmus.JACC. Case reports · 2026Article
- Pulsed Field Ablation Therapy Parameters: Enhancing Lesion Depth While Reducing Musculoskeletal Stimulation and Thermal Response in an Irrigated Tip Catheter: A Comprehensive Study Using In Silico, In Vitro, and In Vivo Models.Circulation. Arrhythmia and electrophysiology · 2026Article
- Successful pulsed field ablation for refractory premature ventricular contractions using a novel dual-energy focal catheter: a case report.European heart journal. Case reports · 2026Article
- First-in-human use of the dual-energy SMARTTOUCH™ SF radiofrequency and pulsed field ablation catheter for ventricular arrhythmia treatment.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026Article
- Combined Pulsed Field and Radiofrequency Ablation for Coexisting Atrial Tachycardia During or After Atrial Fibrillation Ablation. Interventional and Clinical Outcomes.Journal of cardiovascular electrophysiology · 2026Article
- Hybrid pentaspline pulsed-field and radiofrequency ablation for left atrial mitral isthmus block: Acute and long-term outcomes.Heart rhythm O2 · 2026Article
- Temperature as a "hidden dose" in pulsed field ablation: toward temperature-aware workflows and reproducible reporting.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026Article
- Thermal preconditioning of targeted tissue enhances pulsed field ablation lesions.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026Article
- Sequential radiofrequency-pulsed field ablation of a refractory right posteroseptal accessory pathway using a dual-energy catheter.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026Article
- Endocardial ablation of a suspected mid-myocardial or epicardial ventricular tachycardia using a lattice tip ablation catheter: A case report.HeartRhythm case reports · 2026Article
- Getting to the point-the use of radiofrequency and pulsed field ablation for ablating a challenging redo accessory pathway using an all-in-one dual energy wide area lattice-tip catheter: a case report.European heart journal. Case reports · 2026Article
- Colocalized radiofrequency and pulsed field ablation of incessant ventricular tachycardia with suspected intramural circuit in ischaemic cardiomyopathy using a 3.5 mm single-tip catheter under eCPR: a case report.European heart journal. Case reports · 2026Article
- Dual-energy lattice-tip catheter for posterior mitral line ablation: acute efficacy and 1-year outcomes.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026Article
- Impact of contact parameters on lesion dimensions during circular Pulsed-Field ablation in ex vivo and in vivo models.Scientific reports · 2026Article
- Local modifications in tissular conditions before PFA increases acute lesion size.Heart rhythm O2 · 2026Article
- From Shots to Shocks: When Ethanol Isn't RF's Friend-Pericardial-Esophageal Fistula After Combined Ethanol and Radiofrequency Ablation.JACC. Case reports · 2026Article
- Electricity-Based Locoregional Cancer Therapies and Their Associated Drug Delivery Technologies: From Principles of Action to Clinical Implications.Biomaterials research · 2026Review
- Latest Advances and Ongoing Challenges in Pulsed Field Ablation.Arrhythmia & electrophysiology review · 2026Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSequential application of radiofrequency with pulsed field (PF) ablation may increase lesion depth while preserving the advantages of PF. The study's aim was to determine lesion dimensions of sequential, colocalized radiofrequency and PF ablation.
methodsA preclinical study using swine (n=4) performed lesions in the right/left ventricles. Ablations were performed with a force-sensing 3.5-mm irrigated-tip ablation catheter using a generator delivering both radiofrequency and PF. PF was delivered using unipolar, biphasic pulses at a standard dose (PF index, 300) with 4-mL/min irrigation. Radiofrequency was delivered at 50 W for 10 s (15 mL/min). Lesions were created by applying colocalized radiofrequency followed by sequential application of PF on the same location, PF followed by sequential application of radiofrequency on the same location, PF alone, or radiofrequency alone. Tissue was collected after 2 hours for lesion assessment. Results are mean±SD.
resultsForty-five lesions were analyzed. The lesion depth of radiofrequency alone was 4.9±0.8 mm. The mean lesion depth and width for PF alone were 3.5±0.6 and 5.1±1.8 mm. Lesion depths for combined applications were significantly greater versus PF alone (6.2±1.8 mm radiofrequency followed by sequential application of PF on the same location; 5.7±1.3 mm PF followed by sequential application of radiofrequency on the same location;
conclusionsCombined, colocalized radiofrequency and PF, irrespective of order, show significantly increased lesion size compared with the same dose of PF or radiofrequency alone.
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